Bioactive Products
| Cat. No. | Information |
| CFN99553 | Tetrahydropalmatine Tetrahydropalmatine, a plant alkaloid used as an ingredient in dietary supplement products, is a potent and selective D1 receptor antagonist. Tetrahydropalmatine shows a promyogenic effect by upregulation of p38MAPK, Akt resulting in enhanced MyoD activation, it can effectively protect endothelial cells against γ-irradiation injury. Tetrahydropalmatine has a potential as a therapeutic candidate to prevent fibrosis and improve muscle regeneration and repair and applied to the prevention of endothelial cell dysfunctions associated with ionizing irradiation-induced lung injury. |
| CFN99621 | Marmin Marmin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and secondarily due to the prevention of the effects of endogenous acetylcholine and histamine. It can inhibit contraction of the guinea-pig tracheal smooth muscle, especially by interfering histamine receptor, inhibiting the histamine release from mast, inhibiting intracellular Ca2+ release from the intracellular store and the Ca2+ influx through voltage-dependent Ca2+ channels. Marmin shows a cell-growth inhibitory effect against L1210 and K562 in vitro.S-trans-Marmin shows potent antibacterial, fungicidal, and algicidal properties. Marmin, skimmianine, aegeline, aurapten, zeorin, and dustanin are potential to develop as antihistamine agents, especially as histamine H1 receptor antagonists by interacting with amino acid residues, Asp107, Lys179, Lys191, Asn198, and Trp428 of histamine H1 receptor. |
| CFN99742 | 5-Hydroxytryptophan 5-Hydroxytryptophan (5-HTP) is the precursor of serotonin , has been widely used as a dietary supplement to raise serotonin level, it is an effective drug against depression, insomnia, obesity, chronic headaches, etc. 5-HTP supplementation can inhibit endothelial serotonylation, leukocyte recruitment, and allergic inflammation, it also can reduce the symptoms of anxiety/depression of that patients with allergy/asthma. 5-HTP may be involved in inducing the female to stay in copula and delay egg-laying to prevent re-mating of the female. |
| CFN99894 | Isohyenanchin Isohyenanchin is the potent antagonist of RDLac homo-oligomers, it is also a weak antagonist of ionotropic GABA receptors. |
| CFN99963 | Pseudoginsenoside F11 Pseudoginsenoside F11, a novel partial PPAR γ agonist, can promote adiponectin oligomerization and secretion in 3T3-L1 adipocytes and inhibit obesity-linked phosphorylation of PPAR γ at Ser-273 by Cdk5. It possesses significant neuroprotective activity, has been demonstrated to antagonize the learning and memory deficits induced by scopolamine, morphine and methamphetamine in mice; it also antagonizes the development of analgesia tolerance to morphine and blocks the development of morphine-induced behavioral sensitization via its effect, at least partially, on the glutamatergic system in the mPFC. |
