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  • Bioactive Products
    Catalog No. Information
    CFN99716 Palmitic acid

    1. Palmitic acid induces down-regulation of APOM expression, is mediated via the PPAR╬▓/╬┤ pathway.
    2. Palmitic acid induces anxiety-like behavior in mice while increasing amygdala-based serotonin metabolism.
    3. Palmitic acid induces degeneration of myofibrils and modulate apoptosis in rat adult cardiomyocytes.
    4. Many of the deleterious effects of high-fat diets, specifically those enriched with palmitic acid, are CNS mediated via PKC-theta activation, resulting in reduced insulin activity.
    5. Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytes.
    6. Palmitic acid induces apoptosis in the human leukemic cell line MOLT-4 at 50 micrograms/ml, it also shows in vivo antitumor activity in mice, suggesting that palmitic acid may be a lead compound of anticancer drugs.
    CFN00085 Lavendustin A

    1. Lavendustin A and hormothamnione exhibit cytotoxic effects on tumor cell lines.
    2. Lavendustin A is a potent tyrosine kinase inhibitor of the epidermal growth factor (EGF) receptor, and an angiogenesis inhibitor.
    3. Lavendustin A is a hyperbolic mixed-type inhibitor with respect to both ATP and the peptide substrate, with a major effect on the binding affinities for both substrates.
    4. Lavendustin A at 0.1 nM-1 microM causes a concave-shaped inhibition of the insulin release stimulated by 7 mM glucose, the inhibitory effect can be overcomed by higher concentrations of glucose.
    CFN97005 Sissotrin

    1. Sissotrin can impair glucose tolerance.