Bioactive Products
| Cat. No. | Information |
| CFN97011 | Tagitinin F Tagitinin F possesses antileukemic activity; it also shows in vitro leishmanicidal activities against Leishmania braziliensis promastigotes and amastigotes. |
| CFN97057 | Neridienone B Neridienone B has significant effects on calcein accumulation. Neridienone exhibits significant leishmanicidal activity against amastigotes of L. mexicana. |
| CFN97118 | Phebalosin Phebalosin displays 50% effective concentrations (EC(50)) of 14.1 microg/mL against axenic amastigote forms of Leishmania panamensis. It also displays cytotoxicity (IC(50)) at concentrations of 20.7 microg/mL on human promonocytic U-937 cells. |
| CFN97246 | Quassin Quassin has female anti-fertility properties, possibly acting via inhibition of estrogen secretion. Quassin alters the immunological patterns of murine macrophages through generation of nitric oxide to exert antileishmanial activity. It also exhibits P. falciparum inhibitory activity (IC50=0.06 micro g/ml, 0.15 micro M). Quassin possesses anti-anaemic property, it can significantly increase red blood cell count, pack cell volume and haemoglobin concentration. |
| CFN90426 | Mevastatin Mevastatin inhibits HMGCR (HMG-CoA reductase) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. Mevastatin inhibits the differentiation of TAO derived orbital preadipocytes by blocking PPAR-gamma mRNA expression. Mevastatin induces cell growth inhibition and apoptosis in SACC cells, it triggers the phosphorylation of the EGFR and inhibits the c-Jun N-terminal kinase pathway. |
