Bioactive Products
| Cat. No. | Information |
| CFN99822 | Dehydroabietic acid Dehydroabietic acid , a major poison to fishes in pulp and paper mill effluents, which could be useful in improving the diabetic wound healing, it can reverse several cell responses stimulated by TNF-α, including the activation of FOXO1 and the TGF-β1/Smad3 signaling pathway. Dehydroabietic acid derivatives displays antisecretory and antipepsin effect, have gastroprotective activity in the HCl/EtOH-induced gastric lesions in mice as well as for cytotoxicity in human lung fibroblasts (MRC-5) and human epithelial gastric (AGS) cells. |
| CFN99866 | Sitoindoside I Sitoindoside I has anti-ulcerogenic activity. |
| CFN98023 | 13(18)-Oleanen-3-one δ-Amyrone(13(18)-Oleanen-3-one), a specific inhibitor of cyclooxygenase-2, possesses anti-inflammatory effects, which may be relevant to the regulation of COX-2; it exerts its protective effect on experimental gastric ulcer by inhibiting NF-κB signaling pathways, which subsequently reduces overproduction of the inducible enzymes iNOS and suppresses the release of the inflammatory factors TNF-α, IL-6 and NO. δ-Amyrone has protective activity on LPS-induced endotoxic shock, which is attributed to reducing NO production and mediating the pro-inflammatory cytokines, inhibited NF-κB expression. |
| CFN98083 | Vindoline Vindoline is a chemical precursor to vinblastine and exhibits antimitotic activity by inhibiting microtubule assembly, it also has anti-ulcer activity. Vindoline can enhance the glucose-stimulated insulin secretion (GSIS) in MIN6 cells with the EC50 value of 50.2uM; it has relaxant effects in isolated rat renal arteries, it can dilate renal arteries in vitro through one or more pathways including inhibition of calcium entry,TEA+-sensitive potassium channel or protein kinase pathways in vascular smooth muscle cells. |
| CFN98118 | Patchouli alcohol Patchouli alcohol has anti-inflammatory, neuroprotective, anti-cancer, anti-oxidant, gastroprotective, immunomodulatory, and antibacterial effects, which may be mediated, at least in part, by down-regulation of the mRNA expression of a panel of inflammatory mediators, such as TNF-α, IL-1β, IL-6, iNOS and COX-2. Patchouli alcohol significantly accelerates the recovery of the UV-induced skin lesions, evidently through anti-oxidant and anti-inflammatory action, as well as down-regulation of the MMP-1 and MMP-3 expression. |
