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Bioactive Products
Cat. No. Information
CFN98891 1,3,5-Trihydroxy-4-prenylxanthone

1,3,5-Trihydroxy-4-prenylxanthone is a relatively potent inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 3.0 μM; it shows in vitro inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 56.3plusmn;0.4 and 46.0plusmn;0.3 M, respectively. 1,3,5-Trihydroxy-4-prenylxanthone inhibits LPS-induced NF-κB and AP-1 activations by interfering with the posttranslational modification (phosphorylation and/or ubiquitinylation) of IRAK-1 in the cell membrane to impede TAK1-mediated activation of IKK and MAPKs signal transduction.
CFN00148 Anisodine

Anisodine is a traditional anticholinergics, it and anisodamine possess alpha 1-adrenoceptor blocking properties, they are widely used in the People's Republic of China for the management of acute circulatory shock . Anisodine can protect optic nerve of primary open angle glaucoma (POAG) through improving the visual function and blood supply of optic nerve. The combination of Anisodine and citicoline with standard steroid and mannitol therapy appears to be effective in the treatment of early optic nerve contusion.
CFN00155 Baogongteng A

Baogongteng A and Baogongteng C are the major toxic chemical compounds of the Erycibe species. Baogongteng A analogs as effective muscarinic agonists or antagonists in clinical use.Baogongteng A is a new tropane alkaloid used for treating glaucoma, synthetic baogongteng A also shows myotic activities in rabbits, but the potency is half of that of the natural product.
CFN97052 Vasicine

Vasicine, a potential natural cholinesterase inhibitor, has been in development for treatment of Alzheimer's disease. Vasicine can regulate the inflammatory reaction, have great potentials to develop safe medications for respiratory and reproductive medicine.Vasicine is also oxytocic and abortifacient agents.
CFN00209 Tropine nonanoate

Tropine nonanoate displays antimuscarinic action.