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Bioactive Products
Cat. No. Information
CFN92818 Ginsenoside Rk2

Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities. Ginsenoside Rk1 can strongly inhibit permeability induced by VEGF, advance glycation end-product, thrombin, or histamine in human retinal endothelial cells, it reduces the vessel leakiness of retina in a diabetic mouse model; this anti-permeability activity of Rk1 is correlated with enhanced stability and positioning of tight junction proteins at the boundary between cells; Rk1 induces phosphorylation of myosin light chain and cortactin, which are critical regulators for the formation of the cortical actin ring structure and endothelial barrier.
CFN92888 Nothofagin

Nothofagin has antioxidant, and antithrombotic activities, it possesses anti-inflammatory activity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. Nothofagin may have significant benefits in the treatment of diabetic complications. Nothofagin has potential to as an anti-sendothelial cell protein C receptor shedding reagent against phorbol-12-myristate 13-acetate and cecal ligation and puncture -mediated endothelial cell protein C receptor shedding.
CFN96022 Paeoniflorigenone

Paeoniflorigenone is a depolarizing neuromuscular blocking agent, being similar to succinylcholine.Paeoniflorigenone is cytotoxic and induces apoptosis selectively in the cancer cell lines. Paeoniflorigenone shows anti-inflammatory effects, it may take part in improving blood circulation by inhibiting ether platelet aggregation and/or blood coagulation.
CFN90569 Tranexamic acid

Tranexamic acid is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM. Tranexamic acid appears to be a promising drug for the prevention and treatment of PPH after both vaginal and caesarean delivery, it can reduce mortality due to traumatic bleeding by a third, without apparent safety issues.
CFN90662 Benzoyloxypeoniflorin

Benzoyloxypeoniflorin contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coagulation.