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Bioactive Products
Cat. No. Information
CFN98758 Imperatorin

Imperatorin is an effective of NO synthesis inhibitor (IC50=9.2 μmol), which also is a BChE inhibitor (IC50=31.4 μmol); it is a weak agonist of TRPV1 with EC50 of 12.6±3.2 μM. Imperatorin is a potent myorelaxant agent and acts as a calcium antagonist on vascular smooth muscle. Imperatorin has anticonvulsant, anti-inflammatory, anti-oxidant, neuroprotection, and anti-cancer effects, it also has been used in herbal formulations for the treatment of hypertension and cardiovascular diseases. Imperatorin dampens neuronal excitability by inhibiting voltage-gated Na + channels (VGSC), and blocks the HSP27 and HSP72 gene expression.
CFN98763 Sphondin

Sphondin may have anticonvulsant, anti-inflammatory, and anti-proliferative activities, it may act as a potent inhibitor of NO production under tissue-damaging inflammatory conditions, it also possesses an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells through suppression of NF-kappaB activity. Sphondin, 8-methoxypsoralen, and khellin have delayed phototoxic effects inAedes aegypti.
CFN98889 Coixol

Coixol acts as a central muscle relaxant with an anti-convulsant effect; it can regulate gene expression, production and secretion of mucin, by directly acting on airway epithelial cells. Coixol interacts with the pituitary to stimulate reproduction in voles, it also has the ability to interact with FSH to stimulate follicular development and increase ovulation.
CFN97083 Morusin

Morusin exhibits antinociceptive, analgesic, anticonvulsant, antibacterial, and antitumor activities. Morusin can inhibit NF-κB and STAT3 activity, activate caspases activity, and restorate GABA level.
CFN90160 Methysticin

Methysticin is a potent NF-kappaB inhibitor in kava with minimum toxicity, it possesses hepatotoxic, anticonvulsant and neuroprotective properties, it contributes to CYP1A1 induction.