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  • Bioactive Products
    Antidepressant Compound Library
    A unique collection of 32 Antidepressant natural compounds
    Catalog No: B72a10 Antidepressant Compound Library
    Screening Details
    Size: 1mg/well * 32 Compounds
    2mg/well * 32 Compounds
    Catalog No. Information
    CFN99340 Auraptenol

    1. Auraptenol possesses robust antidepressant-like efficacy in mice.
    2. Auraptenol attenuates vincristine-induced mechanical hyperalgesia through serotonin 5-HT1A receptors, it has potential to be a novel analgesic for the management of neuropathic pain.
    3. Auraptenol shows high inhibitory activities against larval settlement of Balanus albicostatus with EC50values of 3.38 ug m/L.
    CFN99399 Protopine

    Protopine acts as a potent inhibitor of thromboxane synthesis and PAF with hepatoprotective, antidepressant, antioxidant, antispasmodic and relaxant properties. Protopine is also a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines. Protopine blocks phosphorylation of mitogen-activated protein kinases (MAP kinases) and also blocks activation of a nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB).
    CFN99154 Liquiritin

    Liquiritin possesses antidepressant-like, neuroprotective , antioxidant, antiapoptosis, anti-inflammatory and anti-cancer abilities. Liquiritin can attenuate advanced glycation end products-induced endothelial dysfunction via RAGE/NF-κB pathway in human umbilical vein endothelial cells, it may be a promising agent for the treatment of vasculopathy in diabetic patients.
    CFN99155 Isoliquiritin

    Isoliquiritin has significant antidepressant-like, antifungal and anti-cancer activities. It induces apoptotic cell death through upregulating p53 and p21 in the A549 non-small cell lung cancer cells and inhibit the p53-dependent pathway and showed crosstalk between Akt activities.
    CFN99188 Hypericin

    Hypericin is a photosensitive antiviral with anticancer and antidepressant agent . It can inhibit tyrosine kinases with IC50 of 7.5 μM. It can induce both apoptosis and necrosis in a concentration and light dose-dependent fashion, and inhibit RANKL-mediated osteoclastogenesis via affecting ERK signalling in vitro and suppresses wear particle-induced osteolysis in vivo.