Bioactive Products
Cat. No. | Information |
CFN99473 | Conophylline Conophylline is a novel differentiation inducer for pancreatic β cells, can increase the numbers of ductal cells positive for pancreatic-duodenal-homeobox protein-1 and islet-like cell clusters. Conophylline suppresses pancreatic stellate cells and improves islet fibrosis in Goto-Kakizaki rats. It protects cells in cellular models of neurodegenerative diseases by inducing mTOR-independent autophagy. |
CFN99475 | Neotuberostemonine Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages. NTS demonstrates antitussive properties in guinea pigs. |
CFN99581 | Neferine Neferine, a autophagy inducer, which has anti-amnesic, sedative, anti-anxiety, antidepressant, cardioprotective, anti- pulmonary fibrosis,anti-cancer, antioxidant and anti-inflammatory capacities. It inhibited ChEs, BACE1, NF-kappaB, PI3K/Akt/mTOR pathway, Neferine has effects similar to rosiglitazone in decreasing fasting blood glucose, insulin, TG, TNF-alpha and enhancing insulin sensitivity in insulin resistant rats. |
CFN99805 | Oxymatrine Oxymatrine has exhibited anti-hepatitis virus infection, anti-hepatic fibrosis, anti-inflammation, anti-anaphylaxis and other immune-regulation, it induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome C. It can attenuate diabetes-associated cognitive deficits in rats, which is associated with oxidative stress, inflammation and apoptotic cascades, it is proven to protect ischemic and reperfusion injury in liver, intestine and heart. |
CFN99840 | Myricitrin Myricitrin exhibits hepatoprotective, anti-inflammatory,antioxidant, anti-allergic, antinociception, anxiolytic-like, and antipsychotic-like effects. Myricitrin can be used as a drug candidate for the treatment of cardiovascular diseases, by effectively protecting cells from ox-LDL-induced endothelial cell apoptosis and reducing atherosclerotic plaque formation. Myricitrin is also a nitric oxide (NO) and protein kinase C (PKC) inhibitor that has central nervous system activity. |