Bioactive Products
| A unique collection of 73 Antihyperglycemic natural compounds for high throughput screening (HTS) and high content screening (HCS). | ||
| Catalog No: | B545 | Antihyperglycemic Compound Library Screening Details |
| Size: | 1mg/well * 73 Compounds 2mg/well * 73 Compounds | |
| Cat. No. | Information |
| CFN90394 | Obtusifolin Obtusifolin is a novel anti-breast-cancer bone metastasis agent, which has antioxidant, and antinociceptive properties.Obtusifolin has beneficial effects on the development of diabetic retinopathy via inhibition of accumulation of oxidatively modified DNA and nitrotyrosine in the retina, can help prevent vision loss in diabetic patients. Gluco-Obtusifolin and its aglycone may be useful for the treatment of cognitive impairment, and that its beneficial effects are mediated, in part, by the enhancement of cholinergic signaling. |
| CFN90398 | Siamenoside I Siamenoside I is one of the mogrosides that has several kinds of bioactivities, it exhibits maltase inhibitory effect with the IC50 value of 12 mM. |
| CFN92000 | Kushenol A Kushenol A is a kind of Adenosine 3', 5'-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors, it shows selective alpha-glucosidase inhibitory activity. Kushenol A and kushenol C exhibit inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2). |
| CFN92197 | Mahanimbine Mahanimbine inhibits AChE activity in a dose-dependent manner. Mahanimbine can lower the absorption of dietary fat resulting in dietary fat excretion, it can prevent high-fat diet (HFD)-induced hyperlipidemia and fat accumulation in adipose tissue and liver along with the restricted progression of systemic inflammation and oxidative stress. Mahanimbine and mangiferin increases the glucose utilization in a dose-dependent manner, can prevent obesity and use in management of diabetes. |
| CFN92295 | Chebulagic acid Chebulagic acid is a potent DNA topoisomerase inhibitor, and is also COX-2 and 5-LOX dual inhibitor. Chebulagic acid may be of value as broad-spectrum antivirals for limiting emerging/ recurring viruses known to engage host cell glycosaminoglycans for entry. Chebulagic acid can be used to control blood glucose and manage type 2 diabetes, although clinical trials are needed. |
