Bioactive Products
| A unique collection of 51 Antihypertensive natural compound library for Antihypertensive screening | ||
| Catalog No: | Bb138 | Antihypertensive Compound Library Screening Details |
| Size: | 1mg/well * 51 Compounds 2mg/well * 51 Compounds | |
| Cat. No. | Information |
| CFN97525 | Isomartynoside Isomartynoside has inhibition against the angiotensin converting enzyme (ACE) activities, the IC 50 value is 505±26.7μg/ml, it may have antihypertensive effect. Isomartynoside also shows obvious anti-fatigue activity. |
| CFN90176 | Corilagin Corilagin has antitumour, anti-inflammatory, antioxidant, antifibrotics, antiviral, antibacterial, hepatoprotective, antiatherogenic, and antihypertensive activities. Corilagin reduces the cytotoxicity induced by EV71 or CA16 on Vero cells with and IC50 value of 5.6 and 32.33 μg/mL, respectively; it shows the potential to protect against HSV-1-induced encephalitis, and the beneficial effects may be mediated by inhibiting TLR2 signaling pathways. Corilagin attenuates bleomycin-induced epithelial injury and fibrosis via inactivation of oxidative stress, proinflammatory cytokine release and NF-κB and TGF-β1 signaling; it suppresses the activity of beta-lactamase to some extent. |
| CFN90201 | Allicin Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cells. Allicin could significantly inhibit vascular smooth muscle cells' proliferation and migration induced by insulin, which may be related to the inhibition of the activation of ERK signal path. Allicin is beneficial in reducing blood cholesterol, triglycerides levels and systolic blood pressure in hypercholesterolemic rats, it may beneficially affect two risk factors for atherosclerosis–hyperlipidemia and hypertension. |
| CFN90254 | Berbamine hydrochloride Berbamine hydrochloride and Ver block the calcium-induced contraction of depolarized pig coronary artery strips, indicate that it may competitively antagonize the action of calcium. |
| CFN90256 | Geraniin Geraniin is a TNF-α releasing inhibitor with numerous activities including anticancer, anti-inflammatory, has anti-oxidant , and anti-hyperglycemic activities, with an IC50 of 43 μM. Geraniin presents radioprotective effects by regulating DNA damage on splenocytes, exerting immunostimulatory capacities and inhibiting apoptosis of radiosensitive immune cells and jejunal crypt cells. Geraniin induces Nrf2-mediated expression of antioxidant enzymes HO-1 and NQO1, presumably via PI3K/AKT and ERK1/2 signaling pathways, thereby protecting cells from H2O2-induced oxidative cell death. |
