1. Yohimbine is an alkaloid with stimulant and aphrodisiac effects, helping with erections, particularly in those whose erectile dysfunction is due to psychological causes.
2. Yohimbine hydrochloride is an antagonist to xylazine hydrochloride-ketamine hydrochloride immobilization of white-tailed deer.
3. Yohimbine hydrochloride can block alpha 2-adrenergic and dopamine receptors and stimulate serotonergic receptors, it may possible be an antagonist for fescue toxicosis.
4. Yohimbine hydrochloride, a noradrenaline agonist, can facilitate fear extinction, it is thought that the mechanism of enhanced emotional memory is stimulated through elevated noradrenaline levels.
1. Protodioscin is cytotoxic against most cell lines from leukemia and solid tumors in the NCI's human cancer panel, especially selectively against one leukemia line (MOLT-4), one NSCLC line (A549/ATCC), two colon cancer lines (HCT-116 and SW-620), one CNS cancer line (SNB-75), one melanoma line (LOX IMVI), and one renal cancer line (786 - 0) with GI50 < or = 2.0 microM.
2. Protodioscin appears to possess aphrodisiac activity probably due to its androgen increasing property.
3. Protodioscin has antihyperlipidemic effect, its great availability in various vegetables and medicinal plants will be useful in developing health food supplement(s) and/or drug(s) against hyperlipidemia.
1. 9-Hydroxycanthin-6-one inhibits Wnt signaling through the activation of GSK3β independent of CK1α.
2. 9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as well as SV probably through interfering with Ca2+ mobilization.