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Bioactive Products
Cancer-chemoprevention Compound Library
A unique collection of 39 Cancer-chemoprevention natural compounds
Catalog No: B99 Cancer-chemoprevention Compound Library
Screening Details
Size: 1mg/well * 39 Compounds
2mg/well * 39 Compounds
Cat. No. Information
CFN99919 Piperine

Piperine, an inhibitor of human P-glycoprotein and/or CYP3A4, which has antinociceptive, antiarthritic, antidepressant, hepatoprotective, immunomodulatory , antitumor, anti-oxidative, anti-apoptotic, chemo-protective, and anti-inflammatoryactivities. Administration of piperine appears to reverse preexisting high-fat diet (HFD)-induced hepatic steatosis and insulin resistance, probably by activation of adiponectin-AMPK signalling.
CFN99935 Nomilin

Nomilin has immunomodulatory, antioxidant, anti-human immunodeficiency virus(HIV), cancer chemopreventive, antiangiogenic, anti-obesity and anti-hyperglycemic effects. Nomilin inhibits tumor-specific angiogenesis by downregulating VEGF, NO and proinflammatory cytokine profile and also by inhibiting the activation of MMP-2 and MMP-9. It inhibits osteoclastogenesis in vitro by suppression of NFATc1 and MAPK signaling pathways, indicates that nomilin-containing herbal preparations have potential utility for the prevention of bone metabolic diseases.
CFN99938 Punicalagin

Punicalagin has antifungal , antiviral, anti-atherosclerotic, hepatoprotective , anti-obesity., antiproliferative, anti-apoptotic, anti-inflammatory, and antioxidant effects. It can suppress the phosphorylation of MAPK including p38, c-JNK, and ERK, it also has potently inhibiting the activity of fatty acid synthase with half-inhibitory concentration values (IC 50 ) of 4.50μM.
CFN98203 Pinosylvin

Pinosylvin is likely to act as a pro-angiogenic factor, it has anti-inflammatory activity, it may be utilized as a phytotherapic agent for the prevention of cardiovascular inflammatory diseases. Pinosylvin is an effective inhibitor of neutrophil activity, and is potentially useful as a complementary medicine in states associated with persistent inflammation. Pinosylvin has protection against oxidative stress through the induction of HO-1 in human RPE cells. Pinosylvin has inhibition against White-Rot and Brown-Rot Fungi.
CFN98328 Xanthohumol D

Xanthohumol and xanthohumol D are potent inducers of quinone reductase, suggests that they could be used as chemoprevention agents.