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  • Bioactive Products
    Catalog No. Information
    CFN98237 Strictosamide

    1. Strictosamide may have important effects on inflammation and inflammatory pain.
    2. Strictosamide is slightly toxic to Charles River mouse (LD(50)=723.17 mg/kg), producing CNS depression and kidney toxicity.
    3. Strictosamide has nonsignificant in vitro and in vivo effect on kidney Na(+),K(+)-ATPase activity but produced an in vivo increase of Na(+),K(+)-ATPase activity of brain.
    4. Strictosamide possesses antibacterial and antiviral activities.
    CFN98447 Gardneramine

    1. Gardneramine and hirsutine show a local anesthetic action, they also can inhibit the ganglionic transmission of the dog urinary bladder and that the blockade of the nicotinic receptor plays a main role.
    2. Gardneramine has a mild central depressive effect.
    CFN98472 Mesuaxanthone A

    1. Mesuaxanthone A and mesuaxanthone B are two yellow pigments.
    2. Mesuaxantbone A and mesuaxanthone B produce varying degrees of C.N.S. depression characterised by ptosis, sedation, decreased spontaneous motor activity, loss of muscle tone, potentiation of pentobarbitone sleeping time and ether anaerthesia in mice and rats; they also exhibit anti inflammatory activity both by intraperitoneal and oral routes in rats.
    CFN98767 Reticuline

    1. Reticuline is a key compound in the biosynthetic pathway for isoquinoline alkaloids in plants, which include morphine, codeine and berberine.
    2. L-DOPA and reticuline exposure increases ganglionic morphine levels invivo and in vitro.
    3. Reticuline possesses potent central nervous system depressant action, it (50-100 mg/kg i.p.) can produce alteration of behaviour pattern, prolongation of pentobarbital-induced sleep, reduction in motor coordination and D-amphetamine-induced hypermotility and suppression of the conditioned avoidance response.
    4. (S)-Reticuline can elicit vasorelaxation probably due to the blockade of the L-type voltage-dependent Ca(2+) current in rat aorta, the effect may contribute to the potential cardioprotective efficacy of (S)-reticuline.
    CFN90077 DL-Homocysteic acid

    1. DL-Homocysteic acid application disrupts calcium homeostasis and induces degeneration of spinal motor neurons in vivo.