Science | Nature | Cell | View More
Bioactive Products
Cat. No. Information
CFN00355 Clivorine

Clivorine itself has direct toxicity on HEK293 cells, and phosphorylated JNK may play some role in counteracting the toxicity of Clivorine on HEK293 cells. It has anti-proliferative function in L-02 cells may be due to its inducing cell apoptosis with independent of p53 protein. Clivorine induces hepatotoxicity and acute liver injury, which can be protected by quercetin, trolox and epidermal growth factor via inhibiting apoptotic cell death and ameliorating oxidative stress injury.
CFN00370 Fulvine

Fulvine is a hepatotoxic pyrrolizidine alkaloid. An aqueous solution of Fulvine can produce an acute pancreatopathy with interstitial oedema and secondary hypoxic dystrophy of the acinar cells, when administered at doses of 10 and 20 mg/kg body weight.
CFN00378 Ligularine

Ligularine and clivorine are two hepatotoxic otonecine-type pyrrolizidine alkaloids.
CFN97272 9-Oxo-10,11-dehydroageraphorone

9-Oxo-10,11-dehydroageraphorone has acaricidal activity. It induces hepatotoxicity and cholestasis in rats. 9-Oxo-10,11-dehydroageraphorone also effectively inhibits the proliferation of HeLa cells by arresting the cell cycle transition from S to G2/M phase.
CFN00393 Desacetyldoronine

Desacetyldoronine is a hepatotoxic pyrrolizidine alkaloid.