Bioactive Products
| A unique collection of 60 Toxicity natural compounds for screening | ||
| Catalog No: | Bb201 | Toxicity Compound Library Screening Details |
| Size: | 1mg/well * 60 Compounds 2mg/well * 60 Compounds | |
| Cat. No. | Information |
| CFN97759 | Paclitaxel Paclitaxel is a potent anticancer medication which can promote microtubule (MT) assembly, inhibits MT depolymerization, and changes MT dynamics required for mitosis and cell proliferation. Paclitaxel can induce ototoxicity in rats. |
| CFN90359 | Kaempferol-3-beta-O-glucuronide Kaempferol-3-beta-O-glucuronide has antioxidant activity. Flavonoid glucuronides can be deconjugated by microsomal β-glucuronidase from various human cells. |
| CFN97856 | Annonacin Annonacin is mitochondrial complex I inhibitor, reported to be more toxic than rotenone to mesencephalic neurons; can cause significant cell death in various cancer cell lines. Annonacin induces growth arrest and apoptosis in ERα-related pathways in MCF-7 cells, attenuates MCF-7 xenograft tumor growth while inhibiting ERα, cyclin D1 and Bcl-2 protein expressions in nude mice. Annonacin-induced ATP depletion causes the retrograde transport of mitochondria to the cell soma and induces changes in the intracellular distribution of tau in a way that shares characteristics with some neurodegenerative diseases. |
| CFN92008 | Eurycomanone Eurycomanone has anti-cancer activity, it is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2. |
| CFN92010 | Canthin-6-one N-oxide Canthin-6-one N-oxide has broad spectrum antifungal, leishmanicidal and trypanocidal activities. |
