Natural Products
Praeruptorin B
| Catalog No. | CFN98140 |  |
| CAS No. | 81740-07-0 | |
| Molecular Weight: | 426.46 | |
| Molecular Formula | C24H26O7 | |
| DBs | [PubChem]:274952367 [ChEMBL]: [PCIDB]: |
Standard InChI:
InChI=1S/C24H26O7/c1-7-13(3)22(26)29-20-18-16(11-9-15-10-12-17(25)28-19(15)18)31-24(5,6)21(20)30-23(27)14(4)8-2/h7-12,20-21H,1-6H3/b13-7+,14-8+
Biological Activity
Praeruptorin B has significant P-glycoprotein (Pgp)-inhibition activity.[1]
Praeruptorins B and A have LC 50 values of 34.5 and121.2 ug/ml, respectively, in Artemia salina test . [2]
Product
References
[1] Joshi P, Singh S, Wani A, et al. Medicinal Chemistry Communication, 2014, 5(10):1540-7.
[2] Lu M, Nicoletti M, Battinelli L, et al. Cheminform, 2001, 32(44):417-20.
[3] Zhao D, Zhou T Q, Feng S X, et al. Chinese Traditional Patent Medicine, 2012, 34(10):1908-12.
Product Use Citation
