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Natural Products
Sophora tonkinensis Gapnep.

Sophora tonkinensis is a herb used in traditional Chinese medicine. Sofalcone is an oral gastrointestinal medication and a synthetic derivative of sophoradin, an isoprenyl chalcone found in S. tonkinensis.
A new matrine-type alkaloid, (-)-14 beta-hydroxyoxymatrine (1), was isolated from the roots and rhizomes of Sophora tonkinensis Gapnep. (Leguminosae), together with five known matrine-type alkaloids, (-)-14 beta-hydroxymatrine (2), (+)-oxymatrine (3), (+)-matrine (4), (+)-sophoranol (5), and (-)-5 alpha-hydroxysophocarpine ( 6), as well as with two known cytisine-type alkaloids, (-)-cytisine (7) and (-)- N-methylcytisine (8). Their structures were elucidated by spectroscopic methods. Compounds 1, 5 and 7 showed potent anti-HBV activity with an inhibitory potency against HBsAg secretion of 22.6 %, 31.1 % and 33.2 %, and against HBeAg secretion of 30.4 %, 26.3 % and 27.8 %, respectively.

Sophora tonkinensis Gapnep.
Research products of Sophora tonkinensis Gapnep.
Catalog Product Name CAS Number Manual
CFN98835Matrine519-02-8  PDF
CFN99805Oxymatrine16837-52-8  PDF
CFN99776N-Methylcytisine486-86-2  PDF
CFN99513Cytisine485-35-8  PDF
CFN92067Anagyrine486-89-5  PDF
CFN97160Trifolirhizin6807-83-6  PDF
CFN99746Maackiain19908-48-6  PDF
CFN99156Liquiritigenin578-86-9  PDF
CFN97326Stigmasterol83-48-7  PDF
CFN98913Lupeol545-47-1  PDF
CFN99057Lupeol caffeate103917-26-6  PDF
CFN99962Formononetin485-72-3  PDF
CFN98681Genistein446-72-0  PDF
CFN992572'-Hydroxygenistein1156-78-1  PDF
CFN97720Homopterocarpin606-91-7  PDF
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