Product informatin DBs
alpha-Viniferin
Alpha-viniferin isolated from Caragana chamlagu is a trimer of resveratrol, has anti-inflammatory, anti-oxidant, anti-arthritis, and anti-tumor activities;alpha-viniferin strongly inhibits 7 of the 9 CYP isoforms (except CYP2A6 and CYP2E1); alpha-viniferin strongly inhibits CYP2C19-mediated ...
Lucialdehyde A
Lucialdehydes A-C (1-3) are new lanostante-type triterpene aldehydes, isolated from the fruiting bodies of Ganoderma lucidum, show cytotoxic effects on tumor cells, including Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines.[1]
Tanshinone IIB
Tanshinone IIB (TSB) is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) widely used in the treatment of stroke and coronary heart disease in Asian countries; TSB significantly reduces the DNA laddering caused by staurosporine in a concentration-dependent manner, also supp...
alpha-Cyperone
Alpha-cyperone, a major active compound of Cyperus rotundus, has anti-inflammatory effects with the down-regulation of COX-2 and IL-6 via the negative regulation of the NFκB pathway in LPS-stimulated RAW 264.7 cells.[1] In the presence of subinhibitory concentrations of alpha-cyperone, Hla...
Nodakenetin
Nodakenetin displays the least irritant and least persistent reactions on mouse ears, and exhibits the least cytotoxic capacity against brine shrimp larvae.[1] Nodakenetin angelate, extracted from seeds of Heracleum candolleaum , is used as an antiarthritic and nerve tonic. [2] Nodakenetin has ...
Ganoderic acid TN
23-Dihydroganoderic acid N, a triterpenoid compound, has anticancer effects, shows sensitive to MCF-7 cells among NCI-H460, HeLa, U937, and MCF-7 cells.[1]
Ganoderol B
Ganoderol B with 5α-reductase inhibitory activity and the ability to bind to androgen receptor (AR) can inhibit androgen-induced LNCaP cell growth and suppress regrowth of the ventral prostate induced by testosterone in rats, suggests that ganoderol B might be useful in prostate cancer and ...
Ganoderic acid D
Ganoderic acid D (GD) is the major active triterpenoid in Ganoderma lucidum, a medicinal fungus used daily; biliary rather than renal clearance was the major route of excretion, the metabolic transformation included reduction, monohydroxylation, dihydroxylation, trihydroxylation, oxidation, desat...
Capillarisin
Capillarisin is a novel blocker of STAT3 activation, can inhibit constitutive and inducible STAT3 activation through induction of SHP-1 and SHP-2 tyrosine phosphatases, thus it may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cells.[1] Capillarisin ...
Vicenin -1
Vicenin-1, a flavonol glycoside, has potent platelet aggregation inhibition, antioxidant, radioprotectants and anti-inflammatory activities. [1]
