1beta-Hydroxytorilin | CAS:509078-16-4

1beta-Hydroxytorilin

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Description:

1beta-Hydroxytorilin exhibits cytotoxicity against human A549, SK-OV-3, SK-MEL-2, and HCT15 tumor cells.

In vitro:

Arch Pharm Res. 2006 Feb;29(2):131-4.

Guaiane sesquiterpenoids from Torilis japonica and their cytotoxic effects on human cancer cell lines.[Pubmed: 16526276]

METHODS AND RESULTS:
A new compound 2 and two known guaiane-type sesquiterpenoids were isolated from the methylene chloride-soluble fraction of the methanolic extract of the fruits of Torilis japonica (Umbelliferae) through repeated silica gel and Sephadex LH-20 column chromatography. Their chemical structures were elucidated as torilin (1), 11-acetoxy-8-angeloyloxy-1beta-hydroxy-4-guaien-3-one (1beta-Hydroxytorilin, 2), and 11-acetoxy-8-angeloyloxy-1alpha-hydroxy-4-guaien-3-one (1alpha-hydroxytorilin, 3) by spectroscopic analysis.
CONCLUSIONS:
Compounds 1-3 exhibited cytotoxicity against human A549, SK-OV-3, SK-MEL-2, and HCT15 tumor cells.

1beta-Hydroxytorilin Description

Source:	The fruits of Torilis japonica.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	1beta-Hydroxytorilin
Price:
CAS No.:	509078-16-4
Catalog No.:	CFN96793
Molecular Formula:	C₂₂H₃₂O₆
Molecular Weight:	392.49 g/mol
Purity:	>=98%
Type of Compound:	Sesquiterpenoids
Physical Desc.:	Oil
Source:	The fruits of Torilis japonica.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Sesquiterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.5478 mL	12.7392 mL	25.4784 mL	50.9567 mL	63.6959 mL
5 mM	0.5096 mL	2.5478 mL	5.0957 mL	10.1913 mL	12.7392 mL
10 mM	0.2548 mL	1.2739 mL	2.5478 mL	5.0957 mL	6.3696 mL
50 mM	0.051 mL	0.2548 mL	0.5096 mL	1.0191 mL	1.2739 mL
100 mM	0.0255 mL	0.1274 mL	0.2548 mL	0.5096 mL	0.637 mL

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CFN97446	Alismol	87827-55-2	220.4	C₁₅H₂₄O
CFN99775	Alismoxide	87701-68-6	238.37	C₁₅H₂₆O₂
CFN96326	Guaiol	489-86-1	222.4	C₁₅H₂₆O
CFN99634	Teuclatriol	152110-17-3	256.4	C₁₅H₂₈O₃
CFN98560	Atractyloside A	126054-77-1	448.5	C₂₁H₃₆O₁₀
CFN89350	Isonardoperoxide	205248-65-3	266.33	C₁₅H₂₂O₄
CFN92654	Orobanone	78916-35-5	216.3	C₁₅H₂₀O
CFN92652	Zedoarondiol	98644-24-7	252.4	C₁₅H₂₄O₃
CFN92620	Isoprocurcumenol	102130-90-5	234.3	C₁₅H₂₂O₂