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2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride
2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride
Price:
CAS No.: 139525-77-2
Catalog No.: CFN90089
Molecular Formula: C13H15NO.HCl
Molecular Weight: 237.73 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride Description
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.2065 mL 21.0323 mL 42.0645 mL 84.1291 mL 105.1613 mL
5 mM 0.8413 mL 4.2065 mL 8.4129 mL 16.8258 mL 21.0323 mL
10 mM 0.4206 mL 2.1032 mL 4.2065 mL 8.4129 mL 10.5161 mL
50 mM 0.0841 mL 0.4206 mL 0.8413 mL 1.6826 mL 2.1032 mL
100 mM 0.0421 mL 0.2103 mL 0.4206 mL 0.8413 mL 1.0516 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
SI20050030417T on 11 Feb 2005.
Novel process for synthesizing and a novel crystal form of agomelatin as well as pharmaceutical preparations containing these.[Reference: WebLink]

METHODS AND RESULTS:
Producing agomelatin comprises reacting 7-methoxy-1-tetralone with cyanoacetic acid in presence of organo-ammonium carboxylate catalyst (V), contacting resulting 2-(7-methoxy-3,4-dihydro-1-naphthyl)acetonitrile (VI) with hydrogenation catalyst in presence of allylic compound to give 2-(7-methoxy-1-naphthyl)acetonitrile (VII), hydrogenating (VII) to give 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride (VIII) and acetylating. Producing agomelatin (N-(2-(7-methoxy-1-naphthyl)ethyl)acetamide) comprises: (i) reacting 7-methoxy-1-tetralone with cyanoacetic acid in the presence of an organoammonium carboxylate catalyst of formula (V) while removing water; (ii) contacting the resulting 2-(7-methoxy-3,4-dihydro-1-naphthyl)acetonitrile (VI) with a hydrogenation catalyst in the presence of an allylic compound to give 2-(7-methoxy-1-naphthyl)acetonitrile (VII); (iii) hydrogenating (VII) in the presence of Raney nickel in ethanol and treating the product with hydrochloric acid to give 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride (VIII); and (iv) reacting (VIII) successively with.
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Prunin

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Neohesperidin

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