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20-O-Acetylingenol-3-angelate
20-O-Acetylingenol-3-angelate
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 20-O-Acetylingenol-3-angelate
Price:
CAS No.: 82425-35-2
Catalog No.: CFN93023
Molecular Formula: C27H36O7
Molecular Weight: 472.57 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The seeds of Euphorbia lathyris L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Biological Activity
Description: Reference standards.
20-O-Acetylingenol-3-angelate Description
Source: The seeds of Euphorbia lathyris L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1161 mL 10.5804 mL 21.1609 mL 42.3218 mL 52.9022 mL
5 mM 0.4232 mL 2.1161 mL 4.2322 mL 8.4644 mL 10.5804 mL
10 mM 0.2116 mL 1.058 mL 2.1161 mL 4.2322 mL 5.2902 mL
50 mM 0.0423 mL 0.2116 mL 0.4232 mL 0.8464 mL 1.058 mL
100 mM 0.0212 mL 0.1058 mL 0.2116 mL 0.4232 mL 0.529 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
US 20140350120 A1[P]. 2014.
Topical composition comprising an ingenol derivative and a surfactant-cosolvent mixture.[Reference: WebLink]

METHODS AND RESULTS:
The term “ingenol derivative” is intended to mean an ingenol compound isolated from a species of Euphorbia, in particular from E. peplus, or an ingenol derivative prepared by chemical synthesis or by a semi-synthetic route, e.g. as disclosed in copending application No. PCT/DK2011/000081. Examples of ingenol derivatives that may be included in the present compositions are ingenol-3-angelate, ingenol-5-angelate, ingenol-20-angelate, 20-O-Acetylingenol-3-angelate and 20-deoxy-ingenol-3-angelate.
CONCLUSIONS:
Ingenol-3-angelate, also known as ingenol-3-mebutate or PEP 005, is currently in development for the treatment of actinic keratosis.
Kukoamine A

Catalog No: CFN93215
CAS No: 75288-96-9
Price: $ / mg
Ginkgolide A

Catalog No: CFN99638
CAS No: 15291-75-5
Price: $40/20mg
Astragaloside III

Catalog No: CFN99174
CAS No: 84687-42-3
Price: $268/20mg
Swertisin

Catalog No: CFN90621
CAS No: 6991-10-2
Price: $228/10mg
Ginsenoside Rg3

Catalog No: CFN99969
CAS No: 14197-60-5
Price: $40/20mg
Acanthoside B

Catalog No: CFN97220
CAS No: 7374-79-0
Price: $268/20mg
Pinostrobin chalcone

Catalog No: CFN99878
CAS No: 18956-15-5
Price: $368/20mg
Pinoresinol 4-O-beta-D-glucopyrano...

Catalog No: CFN97180
CAS No: 69251-96-3
Price: $100/20mg
Syringaresinol

Catalog No: CFN92060
CAS No: 487-35-4
Price: $268/10mg
N-p-Coumaroyloctopamine

Catalog No: CFN97706
CAS No: 66648-45-1
Price: $218/10mg
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