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3,5,7-Trihydroxychromone
3,5,7-Trihydroxychromone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 3,5,7-Trihydroxychromone
Price: $368 / 5mg
CAS No.: 31721-95-6
Catalog No.: CFN89191
Molecular Formula: C9H6O5
Molecular Weight: 194.14 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The herbs of Polygonum jucundum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / $202.4 / In-stock
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 3,5,7-Trihydroxychromone exhibits weak antiangiogenic activity.
3,5,7-Trihydroxychromone Description
Source: The herbs of Polygonum jucundum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.1509 mL 25.7546 mL 51.5092 mL 103.0184 mL 128.7731 mL
5 mM 1.0302 mL 5.1509 mL 10.3018 mL 20.6037 mL 25.7546 mL
10 mM 0.5151 mL 2.5755 mL 5.1509 mL 10.3018 mL 12.8773 mL
50 mM 0.103 mL 0.5151 mL 1.0302 mL 2.0604 mL 2.5755 mL
100 mM 0.0515 mL 0.2575 mL 0.5151 mL 1.0302 mL 1.2877 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Animal Research:
Chinese Traditional & Herbal Drugs, 2014, 45(7):900-905.
Chemical constituents from Ampelopsis cantoniensis and their anti-angiogenic activities.[Reference: WebLink]
To study the chemical constituents from Ampelopsis cantoniensis and their antiangiogenesis activities.
METHODS AND RESULTS:
The compounds were isolated and purified by various chromatographic techniques and their structures were elucidated by spectral analysis, the antiangiogenic activities of compounds isolated were evaluated using a zebrafish model. Fifteen compounds were obtained and identified as cantonienol (1), nootkatone (2), aromadendrane-4β,10β-diol (3), abscisic acid (4), 12-oxo-hardwickiic acid (5), betulinic acid (6), platanic acid (7), vanillic acid (8), resveratrol (9), nectandrin B (10), nectandrin A (11), 3,5,7-Trihydroxychromone (12), 5,7,3',4',5'-pentahydroxyflavanone (13), taxifolin (14) and myricitrin (15).
CONCLUSIONS:
Compound 1 is a new sesquiterpene and named as cantonienol. Compounds 2–7 and 10–12 are isolated from the Ampelopsis plants for the first time, and the other compounds are firstly reported in this plant. Compounds 9, 11 and 12 exhibited weak antiangiogenic activity when evaluated using a zebrafish model.
Structure Identification:
Zhongguo Zhong Yao Za Zhi. 2009 Jul;34(13):1690-1.
Chemical constituents in herbs of Polygonum jucundum.[Pubmed: 19873783]
To investigate the chemical constituents in herbs of Polygonum jucundum.
METHODS AND RESULTS:
The 85% ethanol extract was separated by means of silica gel and Sephadex LH-20 column chromatography. The compounds isolated from the plant were identified by physicochemical properties and spectroscopic evidence. Eight compounds were isolated and identified as: quercetin-3'-O-beta-D-galactoside (1), 8-methoxyquercetin (2), pigenin (3), luteolin (4), quercetin (5), 3,5,7-Trihydroxychromone (6), p-hydroxybenzaldehyde (7), beta-sitosterol (8).
CONCLUSIONS:
All compounds were isolated from this plant for the first time, compounds 5- 8 were isolated from the genus Polygonum for the first time.
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