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4-Epi-curcumenol
4-Epi-curcumenol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 4-Epi-curcumenol
Price:
CAS No.: 350602-21-0
Catalog No.: CFN92615
Molecular Formula: C15H22O2
Molecular Weight: 234.3 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Source: The rhizomes of Curcuma zedoaria
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Our products had been exported to the following research institutions and universities, And still growing.
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  • University of Queensland (Australia)
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Standard reference
In vitro:
Heterocycles.2001 May; 55(5).
Inhibitors of Nitric Oxide Production and New Sesquiterpenes, 4-epi-Curcumenol, Neocurcumenol, Gajutsulactones A and B, and Zedoarolides A and B from Zedoariae Rhizoma.[Reference: WebLink]

METHODS AND RESULTS:
Six new guaiane- or secoguaiane-type sesquiterpenes, 4-Epi-curcumenol, neocurcumenol, gajutsulactones A and B, and zedoarolides A and B, were isolated from aqueous acetone extract of Zedoariae Rhizoma (Zingiberaceae), together with 34 sesquiterpenes and two diarylheptanoids. The stereostructures of new sesquiterpenes were elucidated on the basis of chemical and physicochemical evidence, which included nuclear Overhauser effect (NOE) and circular dichroic (CD) spectroscopic analyses.
CONCLUSIONS:
Gajutsulactones A and B, and 14 sesquiterpenes, and two diarylheptanoids were found to inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-activated mouse peritoneal macrophages.
4-Epi-curcumenol Description
Source: The rhizomes of Curcuma zedoaria
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.268 mL 21.3402 mL 42.6803 mL 85.3606 mL 106.7008 mL
5 mM 0.8536 mL 4.268 mL 8.5361 mL 17.0721 mL 21.3402 mL
10 mM 0.4268 mL 2.134 mL 4.268 mL 8.5361 mL 10.6701 mL
50 mM 0.0854 mL 0.4268 mL 0.8536 mL 1.7072 mL 2.134 mL
100 mM 0.0427 mL 0.2134 mL 0.4268 mL 0.8536 mL 1.067 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN98560Atractyloside A126054-77-1448.5C21H36O10
CFN89350Isonardoperoxide205248-65-3266.33C15H22O4
CFN92654Orobanone78916-35-5216.3C15H20O
CFN92652Zedoarondiol98644-24-7252.4C15H24O3
CFN92620Isoprocurcumenol102130-90-5234.3C15H22O2
CFN92647Procurcumenol21698-40-8234.3C15H22O2
CFN91614Epiprocurcumenol127214-97-5234.33C15H22O2
CFN92621Aerugidiol116425-35-5250.3C15H22O3
CFN92789Neoprocurcumenol102130-91-6234.3C15H22O2
CFN96368Torilolone13018-09-2252.4C15H24O3
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