4-Hydroxyalternariol 9-methyl ether | CAS:959417-17-5

4-Hydroxyalternariol 9-methyl ether

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4-Hydroxyalternariol 9-methyl ether Description

Source:	The liquid fermentation of Alternaria sp. Samif01.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Nat Prod Res. 2017 Feb;31(4):387-396

Dibenzo-α-pyrones from the endophytic fungus Alternaria sp. Samif01: isolation, structure elucidation, and their antibacterial and antioxidant activities.[Pubmed: 27388053]

METHODS AND RESULTS:
The EtOAc extract of the liquid fermentation of Alternaria sp. Samif01, an endophytic fungus obtained from Salvia miltiorrhiza Bunge, showed antibacterial activity against several tested bacterial pathogens. Fractionation of this extract led to the isolation of seven dibenzo-α-pyrones (1-7), including one new compound, 2-acetoxy-2-epi-altenuene (1) and one new natural product, 3-epi-dihydroaltenuene A (2). The structures of the new metabolites were elucidated by comprehensive analysis of the spectroscopic data including (1D, 2D) NMR and HRESIMS, while the absolute configuration of 1 was determined by TDDFT-ECD computation.
CONCLUSIONS:
Altenuisol (5), 4-Hydroxyalternariol 9-methyl ether(6), and alternariol (7) showed inhibitory activities against the tested bacteria with minimum inhibitory concentration values in the range of 86.7-364.7 μM. A preliminary structure-antibacterial activity relationship was discussed. In addition, compounds 2, 5 and 6 displayed promising antioxidant effects using DPPH and hydroxyl radical assays. The cytotoxicity of the isolated compounds was evaluated as well.

Product Name	4-Hydroxyalternariol 9-methyl ether
Price:
CAS No.:	959417-17-5
Catalog No.:	CFN89095
Molecular Formula:	C₁₅H₁₂O₆
Molecular Weight:	288.25 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The liquid fermentation of Alternaria sp. Samif01.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antioxidants Compound Library Antibacterial Compound Library Phenols Compound Library Antifection Inhibitor Library

Description:	4-Hydroxyalternariol 9-methyl ether displays promising antioxidant effects. It also shows antibacterial activity against several tested bacterial pathogens with minimum inhibitory concentration values in the range of 86.7-364.7 uM.
Targets:	Antifection

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.4692 mL	17.3461 mL	34.6921 mL	69.3842 mL	86.7303 mL
5 mM	0.6938 mL	3.4692 mL	6.9384 mL	13.8768 mL	17.3461 mL
10 mM	0.3469 mL	1.7346 mL	3.4692 mL	6.9384 mL	8.673 mL
50 mM	0.0694 mL	0.3469 mL	0.6938 mL	1.3877 mL	1.7346 mL
100 mM	0.0347 mL	0.1735 mL	0.3469 mL	0.6938 mL	0.8673 mL

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CFN89161	Dalbergin	482-83-7	268.26	C₁₆H₁₂O₄
CFN91559	6,7-Dimethoxy-4-phenylcoumarin	1857-05-2	282.3	C₁₇H₁₄O₄
CFN96288	Mesuol	16981-20-7	392.5	C₂₄H₂₄O₅
CFN96845	Alternariol	641-38-3	258.22	C₁₄H₁₀O₅
CFN89090	Alternariol monomethyl ether	23452-05-3	272.25	C₁₅H₁₂O₅
CFN91492	Alternariol-trimethylaether	13872-98-5	300.3	C₁₇H₁₆O₅
CFN89095	4-Hydroxyalternariol 9-methyl ether	959417-17-5	288.25	C₁₅H₁₂O₆