5-Hydroxy-1-methoxyxanthone | CAS:27770-13-4

5-Hydroxy-1-methoxyxanthone

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Description:

5-Hydroxy-1-methoxyxanthone, 1,5-dihydroxyxanthone and 6-deoxyjacareubin are all antifungal against Cladosporium cucumerinum, while they show differing degrees of inhibition of monoamine oxidase A and B.

Targets:

MAO | Antifection

In vitro:

Phytochemistry. 1994 Aug;36(6):1381-5.

An antifungal gamma-pyrone and xanthones with monoamine oxidase inhibitory activity from Hypericum brasiliense.[Pubmed: 7765428]

METHODS AND RESULTS:
A new gamma-pyrone (hyperbrasilone), three known xanthones (1,5-dihydroxyxanthone, 5-Hydroxy-1-methoxyxanthone and 6-deoxyjacareubin) and betulinic acid have been isolated from a dichloromethane extract of stems and roots of Hypericum brasiliense. Their structures were established by spectroscopic methods (UV, EI-MS, 1H and 13C NMR) and that of the gamma-pyrone was confirmed by X-ray crystallography.
CONCLUSIONS:
Hyperbrasilone and the xanthones were all antifungal against Cladosporium cucumerinum, while the three xanthones showed differing degrees of inhibition of monoamine oxidase A and B.

5-Hydroxy-1-methoxyxanthone Description

Source:	The stems and roots of Hypericum brasiliense.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	5-Hydroxy-1-methoxyxanthone
Price:
CAS No.:	27770-13-4
Catalog No.:	CFN96278
Molecular Formula:	C₁₄H₁₀O₄
Molecular Weight:	242.2 g/mol
Purity:	>=98%
Type of Compound:	Xanthones
Physical Desc.:	Yellow powder
Source:	The stems and roots of Hypericum brasiliense.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antifungal Compound Library Xanthones Compound Library MAO Inhibitor Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.1288 mL	20.6441 mL	41.2882 mL	82.5764 mL	103.2205 mL
5 mM	0.8258 mL	4.1288 mL	8.2576 mL	16.5153 mL	20.6441 mL
10 mM	0.4129 mL	2.0644 mL	4.1288 mL	8.2576 mL	10.322 mL
50 mM	0.0826 mL	0.4129 mL	0.8258 mL	1.6515 mL	2.0644 mL
100 mM	0.0413 mL	0.2064 mL	0.4129 mL	0.8258 mL	1.0322 mL

CFN89304	1,2,5-Trihydroxyxanthone	156640-23-2	244.20	C₁₃H₈O₅
CFN89295	2,5-Dihydroxy-1-methoxyxanthone	173220-32-1	258.22	C₁₄H₁₀O₅
CFN99684	Subelliptenone G	162473-22-5	244.2	C₁₃H₈O₅
CFN98472	Mesuaxanthone A	3561-81-7	258.2	C₁₄H₁₀O₅
CFN96578	Tovopyrifolin C	34211-53-5	274.23	C₁₄H₁₀O₆
CFN96272	1-Hydroxy-2,3,5-trimethoxyxanthone	22804-49-5	302.3	C₁₆H₁₄O₆
CFN89262	2-Hydroxyxanthone	1915-98-6	212.20	C₁₃H₈O₃
CFN89353	3,4-Dihydroxy-2-methoxyxanthone	6702-55-2	258.22	C₁₄H₁₀O₅
CFN89359	Kielcorin	64280-48-4	436.41	C₂₄H₂₀O₈
CFN96957	Cadensin D	102349-35-9	466.44	C₂₅H₂₂O₉