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7-Epi-10-deacetylcephalomannine
7-Epi-10-deacetylcephalomannine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 7-Epi-10-deacetylcephalomannine
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CAS No.: 78479-12-6
Catalog No.: CFN89395
Molecular Formula: C43H51NO13
Molecular Weight: 789.86 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The needles of Taxus sumatrana.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Description: 7-Epi-10-deacetylcephalomannine is a natural product from Taxus sumatrana.
7-Epi-10-deacetylcephalomannine Description
Source: The needles of Taxus sumatrana.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.266 mL 6.3302 mL 12.6605 mL 25.3209 mL 31.6512 mL
5 mM 0.2532 mL 1.266 mL 2.5321 mL 5.0642 mL 6.3302 mL
10 mM 0.1266 mL 0.633 mL 1.266 mL 2.5321 mL 3.1651 mL
50 mM 0.0253 mL 0.1266 mL 0.2532 mL 0.5064 mL 0.633 mL
100 mM 0.0127 mL 0.0633 mL 0.1266 mL 0.2532 mL 0.3165 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chem Pharm Bull (Tokyo). 1995 Feb;43(2):365-7.
Taxol and its related taxoids from the needles of Taxus sumatrana.[Pubmed: 7728941]

METHODS AND RESULTS:
Through bioassay-guided separation of the chemical constituents of the needles of Taxus sumatrana, taxol (1), cephalomannine (2), and a new taxoid 19-hydroxy-13-oxobaccatin III (8) have been isolated together with 7-epi-10-deacetyltaxol (3), 7-Epi-10-deacetylcephalomannine (4), baccatin III (5), 19-hydroxybaccatin III (6), and 10-deacetyl-13-oxobaccatin III (7).
CONCLUSIONS:
The chemical structure of 8 has been elucidated on the bases of its chemical and physicochemical properties.
CFN96640Taxcultine153415-46-4819.90C44H53NO14
CFN89043N-Methyltaxol C153083-53-5861.97C47H59NO14
CFN96633Taxol C153415-45-3847.95C46H57NO14
CFN893857-Xylosyl-10-deacetyltaxol C90332-65-3938.02C49H63NO17
CFN8904413-O-Cinnamoylbaccatin III220932-65-0716.77C40H44O12
CFN89140Cabazitaxel intermediate1354900-65-4926.02C51H59NO15
CFN98517Docetaxel114977-28-5807.88C43H53NO14
CFN98516N-Debenzoyl-N-(tert-butoxycarbonyl)taxol125354-16-7849.92C45H55NO15
CFN98518Cephalomannine71610-00-9831.91C45H53NO14
CFN90687Deacetyltaxol78432-77-6811.87C45H49NO13
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