| Structure Identification: |
| Journal of the Chinese Chemical Society, 2013 , 49 (3) :433-6. | | Chemical Constituents of the Aerial Part of Celastrus Hypoleucus[Reference: WebLink] |
METHODS AND RESULTS:
Fourteen compounds including eight triterpenoids, 12-oleanaen-3beta-ol (beta-amyrin) (1), 12-oleanaen-3beta-caffeate (2), 9(11),12-oleanadien-3beta-ol (9(11),12-Oleanadien-3-ol,3), 9(11),12-oleanadien-3-one (4), 9(11),12-oleanadien-3beta-caffeate (5), friedela-3-one (friedelin) (6), friedela-3-one-29-ol (7), and 12-gammateraen-3beta-ol (tetrehymanol) (8); one steroid, beta-sitosterol (9); one long-chain acid, octadecadienoic acid (10); two esters, ester of n-octaolecyl-4-hydroxy-cinnamate (11), and ester of n-octadecyl-caffeic acid (12); one diterpene, 8beta,19-dihydroxy-3-oxopimar- 15-ene (13); one sesquiterpene, 1beta,2beta,9alpha-trihydroxy-beta-dihydroagarofuran (14) were isolated from the aerial part of Celastrus hypoleucus, These compounds were characterized and identified by physical and spectral methods.
CONCLUSIONS:
All compounds were isolated for the first time from this plant. Among them 12-oleanaen-3beta- caffeate (2) and 9(11),12-oleanadien-3beta-caffeate (5) are two new compounds, and ester of n-octadecyl-caffeic acid (12) possessed antilipoperoxidative effect by specifically scavenging the hydroxyl free radical (.OH) in vitro. |
|
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)