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Ajugacumbin A
Ajugacumbin A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Ajugacumbin A
Price: $318 / 5mg
CAS No.: 124961-66-6
Catalog No.: CFN92752
Molecular Formula: C27H38O7
Molecular Weight: 474.6 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The herbs of Ajuga ciliata Bunge.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $318 / In-stock
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Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Description: Reference standards.
Ajugacumbin A Description
Source: The herbs of Ajuga ciliata Bunge.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.107 mL 10.5352 mL 21.0704 mL 42.1408 mL 52.6759 mL
5 mM 0.4214 mL 2.107 mL 4.2141 mL 8.4282 mL 10.5352 mL
10 mM 0.2107 mL 1.0535 mL 2.107 mL 4.2141 mL 5.2676 mL
50 mM 0.0421 mL 0.2107 mL 0.4214 mL 0.8428 mL 1.0535 mL
100 mM 0.0211 mL 0.1054 mL 0.2107 mL 0.4214 mL 0.5268 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chinese Chemical Letters, 1996, 7(5):411-414.
Selective reduction of clerodane diterpenoids.[Reference: WebLink]

METHODS AND RESULTS:
The α, β-unsaturated γ-lactones of neo-clerodane diterpenoids teucvidin, teupernin E and Ajugacumbin A were selectively transformed into saturated Y -lactones and unsaturated diol derivatives with NaBE4. These transformations are of interest due to their selective reduction as compared with catalytic hydrogenation and LiAlH4 reduction of these diterpenoid compounds.
CFN92757Ajugamarin L2124961-67-7432.6C25H36O6
CFN92752Ajugacumbin A124961-66-6474.6C27H38O7
CFN92751Ajugamarin F4122587-84-2534.7C29H42O9
CFN91959Ajugalide C853247-64-0450.52C24H34O8
CFN92759Ajugamarin chlorohydrin85447-27-4585.1C29H41ClO10
CFN92755Ajuganipponin A936323-13-6590.7C31H42O11
CFN92753Ajugamarin H1122616-88-0632.8C34H48O11
CFN92754Ajugamarin G1122587-83-1632.8C34H48O11
CFN92756Ajugatakasin A197723-20-9630.7C34H46O11
CFN97439Dihydroajugapitin87480-84-0552.7 C29H44O10
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