Science | Nature | Cell | View More
Natural Products
Allura Red AC
Allura Red AC
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Allura Red AC
Price: $30 / 20mg
CAS No.: 25956-17-6
Catalog No.: CFN90063
Molecular Formula: C18H14N2Na2O8S2
Molecular Weight: 496.42 g/mol
Purity: >=98%
Type of Compound: Miscellaneous
Physical Desc.: Red powder
Source:
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $12.7 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Stanford University (USA)
  • Harvard University (USA)
  • Korea Intitute of Science and T... (Korea)
  • University of Toronto (Canada)
  • Universitas Airlangga (Indonesia)
  • University of Medicine and Phar... (Romania)
  • China Medical University (Taiwan)
  • University of Malaya (Malaysia)
  • University of Cincinnati (USA)
  • Universitas islam negeri Jakarta (Indonesia)
  • Shanghai Institute of Organic C... (China)
  • More...
Package
Featured Products
Tetrahydrocurcumin

Catalog No: CFN90583
CAS No: 36062-04-1
Price: $30/20mg
Dihydroevocarpine

Catalog No: CFN92786
CAS No: 15266-35-0
Price: $268/10mg
Ganoderic acid F

Catalog No: CFN92055
CAS No: 98665-15-7
Price: $318/20mg
Cinnamic acid

Catalog No: CFN99453
CAS No: 140-10-3
Price: $30/20mg
3-Hydroxy-4-methoxycinnamic acid

Catalog No: CFN99135
CAS No: 537-73-5
Price: $30/20mg
L-Aspartic acid

Catalog No: CFN70148
CAS No: 56-84-8
Price: $30/20mg
Jervine

Catalog No: CFN90955
CAS No: 469-59-0
Price: $40/20mg
Sodium houttuyfonate

Catalog No: CFN90975
CAS No: 1847-58-1
Price: $50/20mg
Liensinine

Catalog No: CFN99580
CAS No: 2586-96-1
Price: $100/20mg
Trametenolic acid

Catalog No: CFN92366
CAS No: 24160-36-9
Price: $318/10mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Allura Red AC and amaranth are very important food azo dyes used in food, drug, paper, cosmetic and textile industries.
Targets: Androgen Receptor | Estrogen receptor | Progestogen receptor
In vitro:
J Hazard Mater. 2015 Jun 15;290:34-42.
Decolorization and mineralization of Allura Red AC aqueous solutions by electrochemical advanced oxidation processes.[Pubmed: 25734532]
The decolorization and mineralization of solutions containing 230 mg L(-1) of the food azo dye Allura Red AC at pH 3.0 have been studied upon treatment by electrochemical oxidation with electrogenerated H2O2 (EO-H2O2), electro-Fenton (EF) and photoelectro-Fenton (PEF).
METHODS AND RESULTS:
Experiments were performed with a stirred tank reactor containing a boron-doped diamond (BDD) or Pt anode and an air-diffusion cathode to generate H2O2. The main oxidants were hydroxyl radicals formed at the anode surface from water oxidation and in the bulk from Fenton's reaction between H2O2 and added Fe(2+). The oxidation ability increased in the sequence EO-H2O2 < EF < PEF and faster degradation was always obtained using BDD. PEF process with BDD yielded almost total mineralization following similar trends in SO4(2-), ClO4(-) and NO3(-) media, whereas in Cl(-) medium, mineralization was inhibited by the formation of recalcitrant chloroderivatives.
CONCLUSIONS:
GC-MS analysis confirmed the cleavage of the −N=N− bond with formation of two main aromatics in SO4(2-) medium and three chloroaromatics in Cl(-) solutions. The effective oxidation of final oxalic and oxamic acids by BDD along with the photolysis of Fe(III)-oxalate species by UVA light accounted for the superiority of PEF with BDD. NH4(+), NO3(-) and SO4(2-) ions were released during the mineralization.
Bull Environ Contam Toxicol. 2013 Jan;90(1):22-6.
Genotoxicity assessment of amaranth and allura red using Saccharomyces cerevisiae.[Pubmed: 23132362]
Amaranth (E123) and Allura Red AC (E129), very important food azo dyes used in food, drug, paper, cosmetic and textile industries, were assessed for their genotoxic potential through comet assay in yeast cells. Comet assay was standardized by with different concentration of H(2)O(2).
METHODS AND RESULTS:
Concentrations of Amaranth and Allura red were maintained in sorbitol buffer starting from 9.76 to 5,000 μg/mL and 1 × 10(4) cells were incubated at two different incubation temperatures 28 and 37°C. Amaranth (E123) and Allura Red AC (E129) were found to exhibit their genotoxic effect directly in Saccharomyces cerevisiae. No significant genotoxic activity was observed for Amaranth and Allura Red AC at 28°C but at 37°C direct relation of Amaranth concentration with comet tail was significant and no positive relation was seen with time exposure factor. At 37°C the minimum concentration of Amaranth and Allura Red AC at which significant DNA damage observed through comet assay was 1,250 μg/mL in 2nd h post exposure time.
CONCLUSIONS:
The results indicated that food colors should be carefully used in baking products as heavy concentration of food colors could affect the fermentation process of baking.
In vivo:
Food Chem Toxicol. 2013 Sep;59:86-9.
The synthetic food colouring agent Allura Red AC (E129) is not genotoxic in a flow cytometry-based micronucleus assay in vivo.[Pubmed: 23748052]
The safety of several azo colouring agents, used as food additives, has during the years been questioned. Allura Red AC (E129) has in some publications been classified as genotoxic. In fact, in the European Union, Allura Red AC is permitted as a food additive in human food, but, surprisingly, it was not acceptable as an additive for use in animal feed.
METHODS AND RESULTS:
In this study we have evaluated whether Allura Red AC is genotoxic using a flow cytometer-based micronucleus assay in peripheral blood of mice. Male FVB mice were given a single intra-peritoneal injection of various doses of Allura Red AC and sacrificed at 46 h after treatment. The tested doses were 0, 100, 200, 400, 600, 800, 1000, 1500, and 2000 mg/kg body weight (b.w.). Each dose group constituted three mice, except for in the dose group of 1000 mg/kg b. w., which constituted four mice. Blood samples were collected and the frequency of micronucleated polychromatic erythrocytes (fMNPCE) and the cell proliferation (%PCE) was determined. The analyses did not show any significant difference in the %PCE or in the fMNPCE.
CONCLUSIONS:
Consequently, under the testing circumstances one can conclude that Allura Red AC is not genotoxic.
Allura Red AC Description
Source:
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Clinopodic acid E

Catalog No: CFN95595
CAS No: 159736-38-6
Price: $318/5mg
3-Hydroxy-4',5-dimethoxystilbene

Catalog No: CFN95199
CAS No: 58436-29-6
Price: $318/10mg
Murracarpin

Catalog No: CFN95409
CAS No: 120786-76-7
Price: $413/5mg
Quercetin 7-O-(6''-O-malonyl)-beta...

Catalog No: CFN95208
CAS No: 98767-37-4
Price: $388/5mg
Malabaricone A

Catalog No: CFN95477
CAS No: 63335-23-9
Price: $318/10mg
Hainanic acid B

Catalog No: CFN95526
CAS No: 1637737-46-2
Price: $413/5mg
Vicinin 2

Catalog No: CFN95249
CAS No: 90456-53-4
Price: $368/5mg
Batatasin IV

Catalog No: CFN95319
CAS No: 60347-67-3
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0144 mL 10.0721 mL 20.1442 mL 40.2885 mL 50.3606 mL
5 mM 0.4029 mL 2.0144 mL 4.0288 mL 8.0577 mL 10.0721 mL
10 mM 0.2014 mL 1.0072 mL 2.0144 mL 4.0288 mL 5.0361 mL
50 mM 0.0403 mL 0.2014 mL 0.4029 mL 0.8058 mL 1.0072 mL
100 mM 0.0201 mL 0.1007 mL 0.2014 mL 0.4029 mL 0.5036 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Food Chem. 2015 Mar 1;170:423-9.
Characterisation of interaction between food colourant allura red AC and human serum albumin: multispectroscopic analyses and docking simulations.[Pubmed: 25306366]

METHODS AND RESULTS:
Binding interaction of human serum albumin (HSA) with Allura Red AC, a food colourant, was investigated at the molecular level through fluorescence, ultraviolet-visible, circular dichroism (CD) and Raman spectroscopies, as well as protein-ligand docking studies to better understand the chemical absorption, distribution and transportation of colourants. Results show that Allura Red AC has the ability to quench the intrinsic fluorescence of HSA through static quenching. The negative values of the thermodynamic parameters ΔG, ΔH, and ΔS indicated that hydrogen bond and van der Waals forces are dominant in the binding between the food colourant and HSA.
CONCLUSIONS:
The CD and Raman spectra showed that the binding of Allura Red AC to HSA induces the rearrangement of the carbonyl hydrogen-bonding network of polypeptides, which changes the HSA secondary structure. This colourant is bound to HSA in site I, and the binding mode was further analysed with the use of the CDOCKER algorithm in Discovery Studio.
Tetrahydrocurcumin

Catalog No: CFN90583
CAS No: 36062-04-1
Price: $30/20mg
Dihydroevocarpine

Catalog No: CFN92786
CAS No: 15266-35-0
Price: $268/10mg
Ganoderic acid F

Catalog No: CFN92055
CAS No: 98665-15-7
Price: $318/20mg
Cinnamic acid

Catalog No: CFN99453
CAS No: 140-10-3
Price: $30/20mg
3-Hydroxy-4-methoxycinnamic acid

Catalog No: CFN99135
CAS No: 537-73-5
Price: $30/20mg
L-Aspartic acid

Catalog No: CFN70148
CAS No: 56-84-8
Price: $30/20mg
Jervine

Catalog No: CFN90955
CAS No: 469-59-0
Price: $40/20mg
Sodium houttuyfonate

Catalog No: CFN90975
CAS No: 1847-58-1
Price: $50/20mg
Liensinine

Catalog No: CFN99580
CAS No: 2586-96-1
Price: $100/20mg
Trametenolic acid

Catalog No: CFN92366
CAS No: 24160-36-9
Price: $318/10mg
Tags: buy Allura Red AC | Allura Red AC supplier | purchase Allura Red AC | Allura Red AC cost | Allura Red AC manufacturer | order Allura Red AC | Allura Red AC distributor