|Source:||The roots of Rheum palmatum|
|Biological Activity or Inhibitors:|| 1. Aloe-emodin-8-O-beta-D-glucopyranoside shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.
|Solvent:||Pyridine, Methanol, Ethanol, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||2.3127 mL||11.5634 mL||23.1267 mL||46.2535 mL||57.8168 mL|
|5 mM||0.4625 mL||2.3127 mL||4.6253 mL||9.2507 mL||11.5634 mL|
|10 mM||0.2313 mL||1.1563 mL||2.3127 mL||4.6253 mL||5.7817 mL|
|50 mM||0.0463 mL||0.2313 mL||0.4625 mL||0.9251 mL||1.1563 mL|
|100 mM||0.0231 mL||0.1156 mL||0.2313 mL||0.4625 mL||0.5782 mL|
J Asian Nat Prod Res. 2006 Apr-May;8(3):281-6.
|PTP1B inhibitors from Saussrurea lappa.[Pubmed: 16864436 ]|
|A new lignan glycoside, named 1,5-dihydroxypinoresinol-4'-O-beta-d-glucopyranoside (1), has been isolated from the EtOH extract of the roots of Saussurea lappa, together with twenty known compounds: (+)-1-hydroxypinoresinol-1-O-beta-D-glucopyranoside (2), fraxiresinol-4'-O-beta-D-glucopyranoside (3), (-)-olivil-4''-O-beta-D-glucopyranoside (4), 4-allyl-2,6-dimethoxybenzene-1-O-beta-D-glucopyranoside, syringin, costunolide-15-O-beta-D-glucopyranoside, chlorogenic acid, Aloe-emodin-8-O-beta-D-glucopyranoside (5), rhein-8-O-beta-D-glucopyranoside (6), chrysophanol (7), emodin, dehydrocostus lactone, costunolide, beta-costic acid, reynosin, arbusculin A, alpha-cyclocostunolide, beta-cyclocostunolide, santamarine and magnolialide. Three anthraquinones (5-7) showed moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.|