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Altamycin A
Altamycin A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Altamycin A
Price:
CAS No.: 60202-22-4
Catalog No.: CFN00103
Molecular Formula: C30H43NO9
Molecular Weight: 561.67 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: From Streptomyces sp.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Altamycin A is a kind of antibiotic.
Targets: Antifection
In vitro:
Antibiotiki. 1976 Jun;21(6):487-91.
Actinomyces pneumonicus var. altamicus var. nov., a producer of new altamycin antibiotics.[Pubmed: 942187]
Actinomycete LIA-0788 was isolated from a soil sample.
METHODS AND RESULTS:
By its morphological and cultural features the actinomycete was close to Actinomyces pneumonicus and differed from it in the antibiotic properties. This provided classification of actinomycete LIA-0788 as Act. pneumonicus var. altamicus var nov.
CONCLUSIONS:
The culture produced Altamycin A and altamycin B, new antibiotics. Their physico-chemical characteristics is presented.
Altamycin A Description
Source: From Streptomyces sp.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7804 mL 8.902 mL 17.804 mL 35.6081 mL 44.5101 mL
5 mM 0.3561 mL 1.7804 mL 3.5608 mL 7.1216 mL 8.902 mL
10 mM 0.178 mL 0.8902 mL 1.7804 mL 3.5608 mL 4.451 mL
50 mM 0.0356 mL 0.178 mL 0.3561 mL 0.7122 mL 0.8902 mL
100 mM 0.0178 mL 0.089 mL 0.178 mL 0.3561 mL 0.4451 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Antibiot Med Biotekhnol. 1986 Nov;31(11):835-41.
Physicochemical properties and structure of the nonmacrolide polyene antibiotic altamycin A.[Pubmed: 3813506]

METHODS AND RESULTS:
Altamycin A, an antibiotic described earlier was classified by its physicochemical and biological properties as belonging to the subgroup of polyenic nonmacrolides. Physicochemical properties of Altamycin A and other representatives of nitrogen-containing polyenic nonmacrolides are presented. It is shown that the molecule of the antibiotic contains D-digitoxose (a sugar).
CONCLUSIONS:
The structure of the antibiotic aglycone was determined by the mass spectra of the oxidative degradation products of perhydroantibiotic, methyl heptahydroantibiotic and methyl permethylperhydroaglycone. Unlike alpha-lipomycin, Altamycin A contains the tetraene system of conjugated methylene bonds.
CFN00090Panamycin 607100905-89-3607.86C35H61NO7
CFN00101Aburatubolactam A170894-24-3508.66C30H40N2O5
CFN00103Altamycin A60202-22-4561.67C30H43NO9
CFN00112Cylindramide147362-39-8466.57C27H34N2O5
CFN00114Discodermide134458-00-7482.58C27H34N2O6
CFN00126Antibiotic BU 2313A69774-86-3517.57C27H35NO9
CFN00144Xanthobaccin A227596-81-8510.63C29H38N2O6
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