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Argentinine
Argentinine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Argentinine
Price:
CAS No.: 16625-57-3
Catalog No.: CFN96081
Molecular Formula: C19H21NO2
Molecular Weight: 295.4 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Oil
Source: The herbs of Piper longum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Argentinine exhibits significant activity against Trypanosoma cruzi.
Targets: Antifection
In vitro:
J Nat Prod. 1994 Jul;57(7):890-5.
New aporphine alkaloids from guatteria foliosa.[Pubmed: 7964785]

METHODS AND RESULTS:
Four new alkaloids were obtained from Guatteria foliosa, namely, the noraporphines (-)-3-methoxyputerine [1] and (+)-norguattevaline [2], the more highly oxidized (+)-3-methoxyguattescidine [3], and the oxoaporphine 3-methoxyoxoputerine [4].
CONCLUSIONS:
Among several other known alkaloids also found in this same plant, (-)-3-hydroxynornuciferine, (-)-isoguattouregidine, and Argentinine exhibited significant activity against Trypanosoma cruzi.
Argentinine Description
Source: The herbs of Piper longum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3852 mL 16.9262 mL 33.8524 mL 67.7048 mL 84.631 mL
5 mM 0.677 mL 3.3852 mL 6.7705 mL 13.541 mL 16.9262 mL
10 mM 0.3385 mL 1.6926 mL 3.3852 mL 6.7705 mL 8.4631 mL
50 mM 0.0677 mL 0.3385 mL 0.677 mL 1.3541 mL 1.6926 mL
100 mM 0.0339 mL 0.1693 mL 0.3385 mL 0.677 mL 0.8463 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Nat Prod Res. 2004 Jun;18(3):265-8.
A new dehydroaporphine alkaloid from Papaver fugax.[Pubmed: 15143838]

METHODS AND RESULTS:
A new dehydroaporphine alkaloid (-)-6a,7-dehydrofloripavidine has been isolated from the aerial parts of Papaver fugax Poir. (Papaveraceae) collected from Erzurum (Eastern Anatolia). (-)-Floripavidine (aporphine) and (-)-mecambrine (proaporphine) were isolated as major alkaloids. Other bases present were (+)-salutaridine (promorphinane) and Argentinine (phenanthrene).
CONCLUSIONS:
The presence of Argentinine has been shown for the first time in the Papaveraceae.
Chem Pharm Bull (Tokyo). 2002 Dec;50(12):1613-5.
Chromone and phenanthrene alkaloids from Dennettia tripetala.[Pubmed: 12499602]

METHODS AND RESULTS:
Dennettine, a new 2,6-dimethoxychromone and three known phenanthrene alkaloids (uvariopsine, stephenanthrine and Argentinine) in addition to the phenolic and known compound vanillin were isolated from the roots of Dennettia tripetala.
CONCLUSIONS:
Their structures were determined by physical and spectroscopical one dimensional (1D) and 2D-NMR analysis, including heteronuclear multiple bond correlation and nuclear Overhauser enhancement spectroscopy.
CFN96041Cepharadione A55610-01-0305.3C18H11NO4
CFN91018(-)-Anonaine1862-41-5265.31C17H15NO2
CFN91019Roemerine548-08-3279.33C18H17NO2
CFN91767Fissistigine A70420-58-5311.33C18H17NO4
CFN93031Laetanine72361-67-2313.35C18H19NO4
CFN90492Laurolitsine5890-18-6313.34C18H19NO4
CFN99528Norisoboldine23599-69-1313.35C18H19NO4
CFN96271Norglaucine hydrochloride39945-41-0377.9C20H24ClNO4
CFN96155Dehydroformouregine107633-69-2337.4C20H19NO4
CFN894856-Formyl-1,2,9,10-tetramethoxy-6a,7-dehydroaporphine2101836-45-5367.39C21H21NO5
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