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Asperumine
Asperumine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Asperumine
Price:
CAS No.: 78513-20-9
Catalog No.: CFN00327
Molecular Formula: C18H25NO4
Molecular Weight: 319.40 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Symphytum asperum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
Asperumine Description
Source: The herbs of Symphytum asperum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1309 mL 15.6544 mL 31.3087 mL 62.6174 mL 78.2718 mL
5 mM 0.6262 mL 3.1309 mL 6.2617 mL 12.5235 mL 15.6544 mL
10 mM 0.3131 mL 1.5654 mL 3.1309 mL 6.2617 mL 7.8272 mL
50 mM 0.0626 mL 0.3131 mL 0.6262 mL 1.2523 mL 1.5654 mL
100 mM 0.0313 mL 0.1565 mL 0.3131 mL 0.6262 mL 0.7827 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chemistry of Natural Compounds,1974,10,(4): 483-485.
Refinement of the structure of asperumine[Reference: WebLink]
Asperumine has been isolated from the combined alkaloids ofSymphytum caucasicum.
METHODS AND RESULTS:
The hydrolysis and hydrogenolysis of Asperumine has given heliotridine, acetone, and angelic and asperuminic acids. The structure of Asperumine has been refined on the basis of the products of hydrolysis and hydrogenolysis and also of features of the mass and NMR spectra.
CONCLUSIONS:
It has been established that Asperumine is an isomer of heliosupine in the 2,3,4-trihydroxy-2-methylpentane-3-carboxylic acid moiety.
CFN00318Senampeline A62787-00-2473.52C25H31NO8
CFN00319Senampeline B62860-52-0473.52C25H31NO8
CFN00320Senampeline C62841-11-6473.52C25H31NO8
CFN00321Senampeline D62787-01-3473.52C25H31NO8
CFN003247-Angeloylretronecine6029-82-9237.30C13H19NO3
CFN003259-Angeloylretronecine N-oxide27773-86-0253.30C13H19NO4
CFN00326Rivularine723-78-4237.29C13H19NO3
CFN00327Asperumine78513-20-9319.40C18H25NO4
CFN00329Trachelanthamine14140-18-2285.38C15H27NO4
CFN00330Trachelanthine510-19-0301.38C15H27NO5
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