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(+)-Balanophonin
(+)-Balanophonin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name (+)-Balanophonin
Price: $463 / 5mg
CAS No.: 215319-47-4
Catalog No.: CFN90897
Molecular Formula: C20H20O6
Molecular Weight: 356.36 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The barks of Gmelina arborea.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $312.8 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: (+)-Balanophonin exhibits marginal inhibition on the proliferation of OPM2 and RPMI-8226 cells.
In vitro:
Chin J Nat Med. 2013 Jul;11(4):411-4.
Isolation of cytotoxic compounds from the seeds of Crataegus pinnatifida.[Pubmed: 23845552]
To study the chemical constituents and bioactivity of the seeds of Crataegus pinnatifida.
METHODS AND RESULTS:
The chemical constituents were isolated and purified by macroporous adsorptive resin D101, silica gel, and ODS column chromatography, and preparative HPLC. Their structures were elucidated on the basis of spectroscopic methods. In addition, the cytotoxic activities of compounds 1-4 were investigated on OPM2 and RPMI-8226 cells. Four compounds were obtained and their structures were identified as (7S, 8S)-4-[2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-1-(hydroxymethyl)ethoxy]-3, 5-dimethoxybenzaldehyde (1), (+)-Balanophonin (2), erythro-guaiacylglycerol-β-coniferyl aldehyde ether (3), buddlenol A (4).
CONCLUSIONS:
Compound 1 is a novel norlignan, while compounds 1-4 exhibited marginal inhibition on the proliferation of OPM2 and RPMI-8226 cells.
(+)-Balanophonin Description
Source: The barks of Gmelina arborea.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8062 mL 14.0308 mL 28.0615 mL 56.123 mL 70.1538 mL
5 mM 0.5612 mL 2.8062 mL 5.6123 mL 11.2246 mL 14.0308 mL
10 mM 0.2806 mL 1.4031 mL 2.8062 mL 5.6123 mL 7.0154 mL
50 mM 0.0561 mL 0.2806 mL 0.5612 mL 1.1225 mL 1.4031 mL
100 mM 0.0281 mL 0.1403 mL 0.2806 mL 0.5612 mL 0.7015 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Journal of Wood Science, 2008, 54(6):483-489.
Chemical constituents from Gmelina arborea bark and their antioxidant activity.[Reference: WebLink]
Gmelina arborea Roxb. is a fast-growing species and is known to have been used in traditional Indian medicine. Chemical constituents from the bark have not been reported, although some chemical constituents from part of this plant (heartwood, leaf, and root) are known.
METHODS AND RESULTS:
In this study, the bark meal was successively extracted with acetone and methanol. Fractionation of the acetone extract with n-hexane, diethyl ether, and ethyl acetate and subsequent chromatographic separation of the fractions led to the isolation of four compounds. The diethyl ether-soluble fraction yielded tyrosol [2-(4-hydroxyphenyl)ethanol] (1); (+)-Balanophonin (2), an 8-5' neolignan, with opposite optical rotation to known (-)-balanophonin; and gmelinol (3), a known lignan. The ethyl acetate-soluble fraction afforded a new phenylethanoid glycoside to the best of our knowledge, which was identified as (-)-p-hydroxyphenylethyl[5'"-O-(3,4-dimethoxycinnamoyl)-β-d-apiofuranosyl(1'" [rightward arrow] 6')]-β-d-glucopyranoside (4). From the methanol extract, two known compounds, 2,6-dimethoxy-p-benzoquinone (5) and 3,4,5-trimethoxyphenol (6), were isolated and identified.
CONCLUSIONS:
The 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay of the identifi ed compounds indicated that 3,4,5-trimethoxyphenol (6) exhibited moderate activity.
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