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Broussonol E
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Broussonol E
Price:
CAS No.: 363134-28-5
Catalog No.: CFN91978
Molecular Formula: C25H26O7
Molecular Weight: 438.47 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The leaves of Broussonetia kazinoki
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Broussonol E may show cytotoxic activity against several different cell lines.
In vitro:
J Nat Prod. 2001 Sep;64(9):1206-9.
Five new diprenylated flavonols from the leaves of Broussonetia kazinoki.[Pubmed: 11575957]

METHODS AND RESULTS:
Five new diprenylated flavonols, broussonol A (1), broussonol B (2), broussonol C (3), broussonol D (4), and Broussonol E (5), along with two known compounds, were isolated from an ethanolic extract of the leaves of Broussonetia kazinoki.
CONCLUSIONS:
Their structures were elucidated by chemical and spectral methods. Cytotoxic activities were evaluated against several different cell lines.
Broussonol E Description
Source: The leaves of Broussonetia kazinoki
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2807 mL 11.4033 mL 22.8066 mL 45.6132 mL 57.0164 mL
5 mM 0.4561 mL 2.2807 mL 4.5613 mL 9.1226 mL 11.4033 mL
10 mM 0.2281 mL 1.1403 mL 2.2807 mL 4.5613 mL 5.7016 mL
50 mM 0.0456 mL 0.2281 mL 0.4561 mL 0.9123 mL 1.1403 mL
100 mM 0.0228 mL 0.114 mL 0.2281 mL 0.4561 mL 0.5702 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chinese Traditional & Herbal Drugs, 2014, 45(24):3520-3523.
Chemical constituents from Engelhardtia roxburghiana.[Reference: WebLink]
To study the chemical constituents from the stem bark of Engelhardtia roxburghiana.
METHODS AND RESULTS:
The compounds were isolated and purified by various chromatographic techniques and their structures were elucidated by spectral analysis. Ten compounds were obtained and identified as eudesm-4(15)-ene-1β,6α-diol (1), (4S)-4-hydroxy-1-tetralone (2), (-)-regiolone (3), p-hydroxybenzoic acid (4), kaempferol (5), isolicoflavonol (6), broussoflavonol F (7), Broussonol E (8), kaempferol-3-O-α-L-rhamnoside (9), quercetin-3-O-α-L-rhamnoside (10).
CONCLUSIONS:
Compounds 1, 4, 6–8 are isolated from the Engelhardtia plants for the first time, and the prenylated flavonoids are firstly reported in this genus.
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