Camelliaside A | CAS:135095-52-2 | Manufacturer ChemFaces

Camelliaside A

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Size /Price /Stock	10 mM * 1 mL in DMSO / $177.8 / In-stock
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Description:

Camelliaside A is a natural product from Camellia oleifera Abel.

In vitro:

J Sci Food Agric. 2011 Oct;91(13):2315-21.

Isolation and anti-inflammatory effect of astragalin synthesized by enzymatic hydrolysis of tea seed extract.[Pubmed: 21567414 ]

The application of tea seed extract (TSE) has been widely investigated because of its biological activities. In this paper, two flavonol triglycosides in TSE-Camelliaside A (CamA) and camelliaside B (CamB)-were subjected to hydrolysis in the presence of two commercial enzyme complexes (Pectinex™ series): Smash and Mash.
METHODS AND RESULTS:
Smash hydrolyzed only the xylosyl moiety of CamB, and the main product was kaempferol diglycoside (nicotiflorin, NF). On the other hand, Mash induced the hydrolysis of both CamA and CamB, and kaempferol monoglycoside (astragalin, AS) was found to be a main product. Pure AS with > 96% purity was prepared by enzymatic hydrolysis of TSE using Mash, and the chemical structure of AS was confirmed by (1)H- and (13)C-nuclear magnetic resonance analyses. The prepared pure AS showed anti-inflammatory activities by significantly inhibiting cellular nitrite oxide (IC(50) = 363 µg mL(-1)), prostaglandin E(2) (IC(50) = 134 µg mL(-1)) and interleukin-6 production (IC(50) = 289 µg mL(-1)) by lipopolysaccharide -stimulated RAW 264.7 cells.
CONCLUSIONS:
It was concluded that pure AS can be prepared by enzymatic partial hydrolysis of TSE and employed as an anti-inflammatory material. This is the first study to address the preparation of pure AS from natural sources.

Camelliaside A Description

Source:	The seeds of Camellia oleifera Abel
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

J Sci Food Agric. 2013 Jan;93(2):362-7.

Novel synthesis of leucoside by enzymatic hydrolysis of tea seed extract.[Pubmed: 22777867 ]

The application of tea seed extract (TSE) has been widely investigated owing to its biological activities. In this paper, two flavonol triglycosides found in TSE, Camelliaside A (CamA) and camelliaside B (CamB), were subjected to hydrolysis in the presence of three commercial enzyme complexes of the Pectinex® series, 5XL, XXL and Ultra SP-L (Ultra).
METHODS AND RESULTS:
XXL and 5XL induced stepwise deglycosylation of CamA and CamB to yield kaempferol diglycoside (nicotiflorin), kaempferol monoglycoside (astragalin) and kaempferol, while Ultra produced an additional new compound (1) that had not been observed in earlier studies. Upon hydrolysis of isolated CamA and CamB, compound (1) was obtained only from CamB. Both the molecular ion peak in liquid chromatography/mass spectrometry and the 1H and 13C nuclear magnetic resonance spectra of (1) isolated by Ultra-induced hydrolysis of TSE indicated that (1) was kaempferol 3-O-β-xylopyranosyl (1 → 2)-β-glucopyranoside (leucoside), formed by selective hydrolysis of the rhamnosyl moiety of CamB.
CONCLUSIONS:
Pure leucoside can be prepared by enzymatic partial hydrolysis of TSE. This is the first study to address the synthesis of pure leucoside from a natural source.

Product Name	Camelliaside A
Price:	$318 / 20mg
CAS No.:	135095-52-2
Catalog No.:	CFN93559
Molecular Formula:	C₃₃H₄₀O₂₀
Molecular Weight:	756.66 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Yellow powder
Source:	The seeds of Camellia oleifera Abel
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Flavonoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.3216 mL	6.608 mL	13.216 mL	26.432 mL	33.0399 mL
5 mM	0.2643 mL	1.3216 mL	2.6432 mL	5.2864 mL	6.608 mL
10 mM	0.1322 mL	0.6608 mL	1.3216 mL	2.6432 mL	3.304 mL
50 mM	0.0264 mL	0.1322 mL	0.2643 mL	0.5286 mL	0.6608 mL
100 mM	0.0132 mL	0.0661 mL	0.1322 mL	0.2643 mL	0.3304 mL

CFN95366	Ternatumoside II	1473419-87-2	594.5	C₂₇H₃₀O₁₅
CFN90342	Helicianeoide A	496066-82-1	726.63	C₃₂H₃₈O₁₉
CFN91162	Kaempferol-3-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside	476617-49-9	756.7	C₃₃H₄₀O₂₀
CFN93560	Camelliaside B	131573-90-5	726.6	C₃₂H₃₈O₁₉
CFN90819	Mauritianin	109008-28-8	740.7	C₃₃H₄₀O₁₉
CFN93559	Camelliaside A	135095-52-2	756.66	C₃₃H₄₀O₂₀
CFN91161	Plantanone B	55780-30-8	756.7	C₃₃H₄₀O₂₀
CFN96532	Kaempferol 3-O-rhamninoside	83170-31-4	740.66	C₃₃H₄₀O₁₉
CFN95134	Rhamnocitrin 3-glucoside	41545-37-3	462.4	C₂₂H₂₂O₁₁
CFN95474	Rhamnocitrin 3-galactoside	99878-05-4	462.4	C₂₂H₂₂O₁₁