Cleomiscosin B | CAS:76985-93-8 | Manufacturer ChemFaces

Cleomiscosin B

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Product Name	Cleomiscosin B
Price:	$390 / 5mg
CAS No.:	76985-93-8
Catalog No.:	CFN94004
Molecular Formula:	C₂₀H₁₈O₈
Molecular Weight:	386.36 g/mol
Purity:	>=98%
Type of Compound:	Coumarins
Physical Desc.:	Powder
Source:	The herbs of Paederia scandens (Lour.) Merr
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $351.1 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Cleomiscosin B Description

Source:	The herbs of Paederia scandens (Lour.) Merr
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Biomed Chromatogr. 2009 Apr;23(4):340-56.

Identification and quantification of two antihepatotoxic coumarinolignoids cleomiscosin A and cleomiscosin B in the seeds of Cleome viscosa using liquid chromatography-tandem mass spectrometry.[Pubmed: 18800331 ]

METHODS AND RESULTS:
A sensitive liquid chromatography/electrospray ionization tandem mass spectrometric (LC/ESI-MS/MS) method was developed for the identification and quantification of two antihepatotoxic coumarinolignoids cleomiscosin A and Cleomiscosin B in different extracts of the seeds of Cleome viscosa. The separation of cleomiscosin A and Cleomiscosin B was achieved on an RP(18) column using a solvent system consisting of a mixture of acetonitrile-methanol (1:2, v/v) and acetonitrile-water-formic acid (5:95:0.3, v/v) as a mobile phase in a gradient elution mode. A multiple-reaction monitoring (MRM) method was developed for quantification of cleomiscosin A and Cleomiscosin B in the seed extracts of Cleome viscosa. On the basis of signal-to-noise ratio of 3, the limit of detection in MRM mode for cleomiscosin A and Cleomiscosin B were 1.0 and 4.0 ng/mL respectively. The method was validated in terms of linearity, accuracy and precision for 6 days.
CONCLUSIONS:
The method developed was found to be useful for identification and quantification of cleomiscosin A and Cleomiscosin B in the different extracts of the seeds of Cleome viscosa.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Hepatoprotective Compound Library Antiviral Compound Library Coumarins Compound Library HIV Inhibitor Library

Description:	Cleomiscosins A, B and C exhibit liver-protective properties. Cleomiscosin B shows the potent anti-HIV-1 activity in vitro and also has protective effects on MT4 cells infected by HIV-1(IIIB).
Targets:	HIV

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.5883 mL	12.9413 mL	25.8826 mL	51.7652 mL	64.7065 mL
5 mM	0.5177 mL	2.5883 mL	5.1765 mL	10.353 mL	12.9413 mL
10 mM	0.2588 mL	1.2941 mL	2.5883 mL	5.1765 mL	6.4706 mL
50 mM	0.0518 mL	0.2588 mL	0.5177 mL	1.0353 mL	1.2941 mL
100 mM	0.0259 mL	0.1294 mL	0.2588 mL	0.5177 mL	0.6471 mL

CFN94004	Cleomiscosin B	76985-93-8	386.36	C₂₀H₁₈O₈
CFN90101	8'-Epicleomiscosin A	N/A	386.36	C₂₀H₁₈O₈
CFN97252	Cleomiscosin A	76948-72-6	386.4	C₂₀H₁₈O₈
CFN96997	6-Demethoxycleomiscosin A	121587-20-0	356.33	C₁₉H₁₆O₇
CFN96996	6-Demethoxy-9'-deoxycleomiscosin A	121587-18-6	340.33	C₁₉H₁₆O₆
CFN98388	5'-Demethylaquillochin	305364-91-4	402.4	C₂₀H₁₈O₉
CFN97400	Cleomiscosin C	84575-10-0	416.4	C₂₁H₂₀O₉
CFN95377	Yinxiancaoside C	1159908-74-3	578.5	C₂₇H₃₀O₁₄
CFN99333	Moluccanin	121700-26-3	386.4	C₂₀H₁₈O₈
CFN99334	Moluccanin diacetate	121700-27-4	470.4	C₂₄H₂₂O₁₀