| Structure Identification: |
| J Org Chem. 2003 Oct 17;68(21):7961-6. | | Two novel alkaloids with a unique fused hexacyclic skeleton from Daphniphyllum subverticillatum.[Pubmed: 14535771] |
METHODS AND RESULTS:
Two novel major alkaloids, deoxycalyciphylline B (1) and Deoxyisocalyciphylline B (2) with a unique fused hexacyclic skeleton, together with a quite recently reported alkaloid calyciphylline B (3), were isolated from the stem of Daphniphyllum subverticillatum. Their structures were established by spectral methods and chemical evidence, especially 2D NMR techniques.
CONCLUSIONS:
The structure of 1 was further confirmed by a single-crystal X-ray diffraction determination. | | J Nat Prod. 2006 Jan;69(1):79-82. | | Alkaloids from Daphniphyllum longeracemosum.[Pubmed: 16441073] |
METHODS AND RESULTS:
Four new Daphniphyllum alkaloids, daphnilongeranins A-D (1-4), along with four known ones, daphniphylline, longistylumphylline A, Deoxyisocalyciphylline B, and daphnicyclidin D, were isolated from the leaves and stems of Daphniphyllum longeracemosum. Daphnilongeranin A (1) is the first seco-10,17-longistylumphylline A type Daphniphyllum alkaloid, and daphnilongeranin B (2) is a new C-22 nor-Daphniphyllum alkaloid based on a new C21 skeleton.
CONCLUSIONS:
Their structures and stereochemistry were determined using spectroscopic data and chemical methods. |
|
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