Science | Nature | Cell | View More
Natural Products
Exoticin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Exoticin
Price: $463 / 5 mg
CAS No.: 13364-94-8
Catalog No.: CFN99417
Molecular Formula: C23H26O10
Molecular Weight: 462.5 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Source: The herbs of Murraya exotica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $463 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Gyeongsang National University (Korea)
  • Kamphaengphet Rajabhat University (Thailand)
  • University of Zurich (Switzerland)
  • Shanghai University of TCM (China)
  • University Medical Center Mainz (Germany)
  • Martin Luther University of Hal... (Germany)
  • Instituto de Investigaciones Ag... (Chile)
  • University of Wollongong (Australia)
  • Sapienza University of Rome (Italy)
  • Griffith University (Australia)
  • Aveiro University (Portugal)
  • More...
Package
Featured Products
Esculin

Catalog No: CFN99114
CAS No: 531-75-9
Price: $30/20mg
Alisol B

Catalog No: CFN92406
CAS No: 18649-93-9
Price: $118/20mg
Uridine

Catalog No: CFN97000
CAS No: 58-96-8
Price: $30/20mg
(-)-Catechin gallate(CG)

Catalog No: CFN98504
CAS No: 130405-40-2
Price: $318/20mg
Betulonic acid

Catalog No: CFN98682
CAS No: 4481-62-3
Price: $40/20mg
DL-alpha-Tocopherol

Catalog No: CFN90041
CAS No: 59-02-9
Price: $30/20mg
Ganoderic acid TR

Catalog No: CFN92235
CAS No: 862893-75-2
Price: $368/5mg
Myricitrin

Catalog No: CFN99840
CAS No: 17912-87-7
Price: $40/20mg
Neohesperidin

Catalog No: CFN99125
CAS No: 13241-33-3
Price: $40/20mg
Soyasaponin Ab

Catalog No: CFN90773
CAS No: 118194-13-1
Price: $ / mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Exoticin shows antinociceptive and neuropharmacological activities, it could be considered as a suitable candidate for the development of analgesic and anxiolytic agents.
Exoticin Description
Source: The herbs of Murraya exotica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
3''-Galloylquercitrin

Catalog No: CFN95048
CAS No: 503446-90-0
Price: $368/5mg
Prionanthoside

Catalog No: CFN95206
CAS No: 161842-81-5
Price: $318/5mg
Giganteone C

Catalog No: CFN95484
CAS No: 1071223-56-7
Price: $318/10mg
7-Oxodehydroabietic acid

Catalog No: CFN95411
CAS No: 18684-55-4
Price: $318/5mg
(-)-Epiafzelechin 3-O-gallate

Catalog No: CFN95081
CAS No: 108907-43-3
Price: $388/5mg
Isophysalin G

Catalog No: CFN95328
CAS No: 152221-21-1
Price: $368/5mg
N-Methylcorydalmine

Catalog No: CFN95204
CAS No: 81010-29-9
Price: $398/5mg
Selaginellin F

Catalog No: CFN95029
CAS No: 1340493-24-4
Price: $413/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1622 mL 10.8108 mL 21.6216 mL 43.2432 mL 54.0541 mL
5 mM 0.4324 mL 2.1622 mL 4.3243 mL 8.6486 mL 10.8108 mL
10 mM 0.2162 mL 1.0811 mL 2.1622 mL 4.3243 mL 5.4054 mL
50 mM 0.0432 mL 0.2162 mL 0.4324 mL 0.8649 mL 1.0811 mL
100 mM 0.0216 mL 0.1081 mL 0.2162 mL 0.4324 mL 0.5405 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Animal Research:
Frontiers in Pharmacology, 2018, 9:85.
Polymethoxyflavones from Nicotiana plumbaginifolia (Solanaceae) exert antinociceptive and neuropharmacological effects in mice.[Reference: WebLink]
Polymethoxylavones (PMFs) are known to exhibit significant anti-inflammatory and neuroprotective properties. Nicotiana plumbaginifolia, an annual Bangladeshi herb, is rich in polymethoxyflavones that possess significant analgesic and anxiolytic activities. The present study aimed to determine the antinociceptive and neuropharmacological activities of polyoxygenated flavonoids namely- 3,3′,5,6,7,8-hexamethoxy-4′,5′-methylenedioxyflavone (1), 3,3′,4′,5′,5,6,7,8-octamethoxyflavone (Exoticin) (2), 6,7,4′,5′-dimethylenedioxy-3,5,3′-trimethoxyflavone (3), and 3,3′,4′,5,5′,8-hexamethoxy-6,7-methylenedioxyflavone (4), isolated and identified from N. plumbaginifolia.
METHODS AND RESULTS:
Antinociceptive activity was assessed using the acetic-acid induced writhing, hot plate, tail immersion, formalin and carrageenan-induced paw edema tests, whereas neuropharmacological effects were evaluated in the hole cross, open field and elevated plus maze test. Oral treatment of compounds 1, 3, and 4 (12.5–25 mg/kg b.w.) exhibited dose-dependent and significant (p < 0.01) antinociceptive activity in the acetic-acid, formalin, carrageenan, and thermal (hot plate)-induced pain models. The association of ATP-sensitive K+ channel and opioid systems in their antinociceptive effect was obvious from the antagonist effect of glibenclamide and naloxone, respectively. These findings suggested central and peripheral antinociceptive activities of the compounds. Compound 1, 3, and 4 (12.5 mg/kg b.w.) demonstrated significant (p < 0.05) anxiolytic-like activity in the elevated plus-maze test, while the involvement of GABAA receptor in the action of compound 3 and 4 was evident from the reversal effects of flumazenil. In addition, compounds 1 and 4 (12.5–25 mg/kg b.w) exhibited anxiolytic activity without altering the locomotor responses.
CONCLUSIONS:
The present study suggested that the polymethoxyflavones (1–4) from N. Plumbaginifolia could be considered as suitable candidates for the development of analgesic and anxiolytic agents.
Esculin

Catalog No: CFN99114
CAS No: 531-75-9
Price: $30/20mg
Alisol B

Catalog No: CFN92406
CAS No: 18649-93-9
Price: $118/20mg
Uridine

Catalog No: CFN97000
CAS No: 58-96-8
Price: $30/20mg
(-)-Catechin gallate(CG)

Catalog No: CFN98504
CAS No: 130405-40-2
Price: $318/20mg
Betulonic acid

Catalog No: CFN98682
CAS No: 4481-62-3
Price: $40/20mg
DL-alpha-Tocopherol

Catalog No: CFN90041
CAS No: 59-02-9
Price: $30/20mg
Ganoderic acid TR

Catalog No: CFN92235
CAS No: 862893-75-2
Price: $368/5mg
Myricitrin

Catalog No: CFN99840
CAS No: 17912-87-7
Price: $40/20mg
Neohesperidin

Catalog No: CFN99125
CAS No: 13241-33-3
Price: $40/20mg
Soyasaponin Ab

Catalog No: CFN90773
CAS No: 118194-13-1
Price: $ / mg
Tags: buy Exoticin | Exoticin supplier | purchase Exoticin | Exoticin cost | Exoticin manufacturer | order Exoticin | Exoticin distributor