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    Gambogellic acid
    Gambogellic acid
    Information
    CAS No. 173867-04-4 Price
    Catalog No.CFN93214Purity>=98%
    Molecular Weight628.76Type of CompoundMiscellaneous
    FormulaC38H44O8Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison
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    Biological Activity
    Description: 1. Gambogellic acid has cytotoxic activity, it exhibits inhibitory effect against SMMC-7221cell and A549 cell.
    Gambogellic acid Description
    Source: The herbs of Garcinia hanburyi Hook. f.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi: 10.1016/j.phymed.2017.12.030.

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.5904 mL 7.9522 mL 15.9043 mL 31.8086 mL 39.7608 mL
    5 mM 0.3181 mL 1.5904 mL 3.1809 mL 6.3617 mL 7.9522 mL
    10 mM 0.159 mL 0.7952 mL 1.5904 mL 3.1809 mL 3.9761 mL
    50 mM 0.0318 mL 0.159 mL 0.3181 mL 0.6362 mL 0.7952 mL
    100 mM 0.0159 mL 0.0795 mL 0.159 mL 0.3181 mL 0.3976 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Gambogellic acid References Information
    Citation [1]

    Nat Prod Res. 2017 Apr;31(7):817-821.

    Two new xanthone epimers from the processed gamboge.[Pubmed: 27809607 ]
    Two new xanthones, gambogollic acid (1), epigambogollic acid (2), together with three rare compounds, Gambogellic acid (3), epiGambogellic acid (4) and gambogic acid (5), were isolated from the processed gamboge. The new structures were determined by 1D and 2D NMR spectroscopic analysis. And the cytotoxicity of these five compounds was evaluated against human hepatoma carcinoma and human lung adenocarcinoma cell. Two new compounds showed excellent antitumor activity. All five compounds exhibited inhibitory effect against SMMC-7221cell and A549 cell.
    Citation [2]

    Phytochemistry. 1996 Feb;41(3):815-20.

    SCytotoxic xanthones from Garcinia hanburyi.[Pubmed: 8835458]
    Eleven novel cytotoxic xanthones, gambogin, morellin dimethyl acetal, isomoreollin B, moreollic acid, gambogenic acid, gambogenin, isogambogenin, desoxygambogenin, gambogenin dimethyl acetal, Gambogellic acid and hanburin were isolated together with four known xanthones, gambogic acid, isomorellin, morellic acid and desoxymorellin, from the dry latex of Garcinia hanburyi. The structures were elucidated by a detailed spectroscopic analysis.