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Gambogellic acid
Gambogellic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Gambogellic acid
Price: $318 / 5mg
CAS No.: 173867-04-4
Catalog No.: CFN93214
Molecular Formula: C38H44O8
Molecular Weight: 628.76 g/mol
Purity: >=98%
Type of Compound: Miscellaneous
Physical Desc.: Powder
Source: The herbs of Garcinia hanburyi Hook. f.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $413.4 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Gambogellic acid has cytotoxic activity, it exhibits inhibitory effect against SMMC-7221cell and A549 cell.
In vitro:
Nat Prod Res. 2017 Apr;31(7):817-821.
Two new xanthone epimers from the processed gamboge.[Pubmed: 27809607 ]
Two new xanthones, gambogollic acid (1), epigambogollic acid (2), together with three rare compounds, Gambogellic acid (3), epiGambogellic acid (4) and gambogic acid (5), were isolated from the processed gamboge.
METHODS AND RESULTS:
The new structures were determined by 1D and 2D NMR spectroscopic analysis. And the cytotoxicity of these five compounds was evaluated against human hepatoma carcinoma and human lung adenocarcinoma cell. Two new compounds showed excellent antitumor activity.
CONCLUSIONS:
All five compounds exhibited inhibitory effect against SMMC-7221cell and A549 cell.
Gambogellic acid Description
Source: The herbs of Garcinia hanburyi Hook. f.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.5904 mL 7.9522 mL 15.9043 mL 31.8086 mL 39.7608 mL
5 mM 0.3181 mL 1.5904 mL 3.1809 mL 6.3617 mL 7.9522 mL
10 mM 0.159 mL 0.7952 mL 1.5904 mL 3.1809 mL 3.9761 mL
50 mM 0.0318 mL 0.159 mL 0.3181 mL 0.6362 mL 0.7952 mL
100 mM 0.0159 mL 0.0795 mL 0.159 mL 0.3181 mL 0.3976 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry. 1996 Feb;41(3):815-20.
Cytotoxic xanthones from Garcinia hanburyi.[Pubmed: 8835458]

METHODS AND RESULTS:
Eleven novel cytotoxic xanthones, gambogin, morellin dimethyl acetal, isomoreollin B, moreollic acid, gambogenic acid, gambogenin, isogambogenin, desoxygambogenin, gambogenin dimethyl acetal, Gambogellic acid and hanburin were isolated together with four known xanthones, gambogic acid, isomorellin, morellic acid and desoxymorellin, from the dry latex of Garcinia hanburyi. The structures were elucidated by a detailed spectroscopic analysis.
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p-Hydroxy-cinnamic acid

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CAS No: 7400-08-0
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Xanthotoxol

Catalog No: CFN98016
CAS No: 2009-24-7
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CAS No: 1449-09-8
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Cheilanthifoline

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Soyasaponin Bb

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Astragaloside I

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