Ginkgolic acid C15:0 | CAS:16611-84-0 | Manufacturer ChemFaces

Ginkgolic acid C15:0

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Ginkgolic acid C15:0 Description

Source:	The leaves of Ginkgo biloba L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Kinase Assay:

Journal of Luminescence Volume 132, Issue 5, May 2012, Pages 1207–1214

Spectroscopic studies on the interaction of bovine serum albumin with ginkgolic acid: Binding characteristics and structural analysis[Reference: WebLink]

The interaction between Ginkgolic acid C15:0 and bovine serum albumin (BSA) is investigated by several spectroscopic methodologies.
METHODS AND RESULTS:
At first, the binding characteristics of Ginkgolic acid C15:0 and BSA are determined by fluorescence emission spectra. It is showed that Ginkgolic acid C15:0 quenches the fluorescence of BSA and the static quenching constant KLB is 11.7891×104 L mol−1 s−1 at 297 K. Ginkgolic acid C15:0 and BSA form a 1:1 complex with a binding constant of 9.12×105 L mol−1. Ginkgolic acid C15:0 binds to the Sudlow's drug binding site II in BSA, and the binding distance between them is calculated as 1.63 nm based on the Förster theory. The thermodynamic parameters indicate that the interaction between BSA and Ginkgolic acid C15:0 is driven mainly by hydrophobic forces. On the other hand, structural analysis indicates that Ginkgolic acid C15:0 binding results in an increased hydrophobicity around the tryptophan residues of BSA as revealed by the synchronous fluorescence spectra, and a decrease in α-helix as revealed by the far-UV CD spectra. In addition, ANS, UV–vis and RLS experiments confirmed that Ginkgolic acid C15:0 binding causes a certain structural changes in BSA.
CONCLUSIONS:
These findings provide the binding information between BSA and Ginkgolic acid C15:0), and may be helpful for pharmacokinetics and the design of dosage forms of Ginkgolic acid C15:0.

Product Name	Ginkgolic acid C15:0
Price:
CAS No.:	16611-84-0
Catalog No.:	CFN90339
Molecular Formula:	C₂₂H₃₆O₃
Molecular Weight:	348.52 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The leaves of Ginkgo biloba L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Phenols Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.8693 mL	14.3464 mL	28.6928 mL	57.3855 mL	71.7319 mL
5 mM	0.5739 mL	2.8693 mL	5.7386 mL	11.4771 mL	14.3464 mL
10 mM	0.2869 mL	1.4346 mL	2.8693 mL	5.7386 mL	7.1732 mL
50 mM	0.0574 mL	0.2869 mL	0.5739 mL	1.1477 mL	1.4346 mL
100 mM	0.0287 mL	0.1435 mL	0.2869 mL	0.5739 mL	0.7173 mL

CFN90885	Cytosporone B	321661-62-5	322.4	C₁₈H₂₆O₅
CFN98621	2'-O-Methylperlatolic acid	38968-07-9	458.6	C₂₆H₃₄O₇
CFN97015	Confluentic acid	6009-12-7	500.6	C₂₈H₃₆O₈
CFN99352	Bongardol	123690-76-6	544.9	C₃₆H₆₄O₃
CFN96020	9-Deoxygoniopypyrone	136685-37-5	234.3	C₁₃H₁₄O₄
CFN96048	Goniopypyrone	129578-07-0	250.3	C₁₃H₁₄O₅
CFN98507	Ginkgolic acid C13:0	20261-38-5	320.47	C₂₀H₃₂O₃
CFN90339	Ginkgolic acid C15:0	16611-84-0	348.52	C₂₂H₃₆O₃
CFN90161	Ginkgolic acid C15:1	22910-60-7	346.50	C₂₂H₃₄O₃
CFN98508	Ginkgolic acid C17:1	111047-30-4	374.56	C₂₄H₃₈O₃