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Grandiflorenic acid
Grandiflorenic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Grandiflorenic acid
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CAS No.: 22338-67-6
Catalog No.: CFN97781
Molecular Formula: C20H28O2
Molecular Weight: 300.44 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The herbs of Siegesbeckia orientalis L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Pure Grandiflorenic acid can reproduce the uterine responses induced by zoapatle leaves aqueous extract , suggests that grandiflorenic acid may have antifertility effect.
Targets: Estrogen receptor | Progestogen receptor
In vitro:
J Ethnopharmacol. 1984 Jun;11(1):87-97.
The in vitro effect of grandiflorenic acid and zoapatle aqueous crude extract upon spontaneous contractility of the rat uterus during oestrus cycle.[Pubmed: 6540830]

METHODS AND RESULTS:
Pure Grandiflorenic acid (GA), obtained from the phytochemical work up of this plant reproduced the uterine responses induced by ZACE. The action of zoapatle is discussed in relation to hormonal stage and to a probable adrenergic mechanism involved.
Grandiflorenic acid Description
Source: The herbs of Siegesbeckia orientalis L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

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Sci Adv. 2018 Oct 24;4(10): eaat6994.
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IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3285 mL 16.6423 mL 33.2845 mL 66.569 mL 83.2113 mL
5 mM 0.6657 mL 3.3285 mL 6.6569 mL 13.3138 mL 16.6423 mL
10 mM 0.3328 mL 1.6642 mL 3.3285 mL 6.6569 mL 8.3211 mL
50 mM 0.0666 mL 0.3328 mL 0.6657 mL 1.3314 mL 1.6642 mL
100 mM 0.0333 mL 0.1664 mL 0.3328 mL 0.6657 mL 0.8321 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN97703Kaurenoic acid6730-83-2302.46C20H30O2
CFN97685Pterokaurene L377658-38-9318.46C20H30O3
CFN964813Alaph-Tigloyloxypterokaurene L31588516-87-3416.56C25H36O5
CFN96012Sventenic acid126778-79-8318.5C20H30O3
CFN97982Acetylsventenic acid126737-42-6360.5C22H32O4
CFN97869ent-3Beta-Tigloyloxykaur-16-en-19-oic acid79406-09-0400.6C25H36O4
CFN96212ent-3beta-Hydroxykaur-16-en-19-oic acid66556-91-0318.5C20H30O3
CFN97870ent-3Beta-Angeloyloxykaur-16-en-19-oic acid74635-61-3400.6C25H36O4
CFN976773alpha-Angeloyloxypterokaurene L379406-11-4416.56C25H36O5
CFN97678ent-3beta-Cinnamoyloxykaur-16-en-19-oic acid79406-10-3448.60C29H36O4
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