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Ikshusterol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Ikshusterol
Price:
CAS No.: 34427-61-7
Catalog No.: CFN98452
Molecular Formula: C29H50O2
Molecular Weight: 430.7 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Oil
Source: The herbs of Lycopodium obscurum Linn.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Reference standards.
Ikshusterol Description
Source: The herbs of Lycopodium obscurum Linn.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3218 mL 11.609 mL 23.218 mL 46.436 mL 58.045 mL
5 mM 0.4644 mL 2.3218 mL 4.6436 mL 9.2872 mL 11.609 mL
10 mM 0.2322 mL 1.1609 mL 2.3218 mL 4.6436 mL 5.8045 mL
50 mM 0.0464 mL 0.2322 mL 0.4644 mL 0.9287 mL 1.1609 mL
100 mM 0.0232 mL 0.1161 mL 0.2322 mL 0.4644 mL 0.5805 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Journal of the Chemical Society Perkin Transactions, 1976(1):23.
Structures of eight new triterpenoids and isolation of other triterpenoids and epi-ikshusterol from the stems of Lithocarpus cornea.[Reference: WebLink]

METHODS AND RESULTS:
Eight new triterpenoids from the light petroleum extract of the stems of Lithocarpus cornea(Lour.) Rhed. have been proved to be taraxer-14-ene-3β,29-diol (VIII) and its diacetate (VII), 29-hydroxytaraxer-14-en-3-one (X) and its acetate (IX), 14α-hydroxytaraxeran-3-one (XXIX), taraxerane-3β,14α-diol (XXX), 22-hydroxy-21αH-hopan-3-one (XXIII), and lup-20(29)-ene-3β,27-diol (XXXII).
CONCLUSIONS:
Other triterpenoids isolated from the same extract, besides those already reported 1 were lupeol, betulin, and myricadiol (I). The steroid epi-Ikshusterol (stigmast-5-ene-3β,7β-diol)(XXXVII) was also obtained.
Chinese Traditional and Herbal Drugs,2001, 32(11):964-966.
Studies on chemical constituents of Adenophora wawreana.[Reference: WebLink]
To study systematically on the chemical constituents of the roots of Adenophora wawreana Zahibr.
METHODS AND RESULTS:
The chemical constituents were extracted and isolated systematically with solvents and silica gel chromatography Their structures were determined on the basis of spectral data (IR, 1HNMR, 13 CNMR and MS). Twelve compounds were obtained, nine of them were identified as β sitosteryl hexadecanoate (Ⅰ), β sitosteryl octadecanoate (Ⅱ), α amyrin acetate (Ⅲ), lupeol acetate (Ⅳ), lupenone (Ⅵ), friedelin (Ⅶ), β sitosterol (Ⅸ), Ikshusterol (Ⅹ) and daucosterol ( ⅩⅡ ).
CONCLUSIONS:
All of them were obtained for the first time from A wawreana and compounds Ⅰ, Ⅱ, Ⅲ, Ⅳ, Ⅶ were obtained for the first time from Adenophora Fisch.
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