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Isonicoteine
Isonicoteine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Isonicoteine
Price:
CAS No.: 581-50-0
Catalog No.: CFN00440
Molecular Formula: C10H8N2
Molecular Weight: 156.19 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Liquid
Source: The aerial part of Anabasis aphylla L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Biological Activity
Description: Reference standards.
In vitro:
Anal Chem. 2013 Mar 19;85(6):3380-4.
Application of GC-MS/MS for the analysis of tobacco alkaloids in cigarette filler and various tobacco species.[Pubmed: 23394466]
This publication reports the first known use of gas chromatography-tandem mass spectrometry for the quantitation of five minor tobacco alkaloids (nornicotine, myosmine, anabasine, anatabine, and Isonicoteine) in various tobacco samples.
METHODS AND RESULTS:
A summary of the concentrations of these minor alkaloid levels in the filler from 50 popular cigarette brands were found to be 659-986 μg/g nornicotine, 8.64-17.3 μg/g myosmine, 127-185 μg/g anabasine, 927-1390 μg/g anatabine, and 23.4-45.5 μg/g Isonicoteine. Levels of minor alkaloids found in reference cigarettes (1R5F, 2R4F, 3R4F, CM4, and CM6) as well as burley, flue-cured, oriental, reconstituted, and Nicotiana rustica and Nicotiana glauca tobacco types are also reported.
CONCLUSIONS:
Quantitation of the minor tobacco alkaloids is important because the alkaloids have been shown to be precursors of carcinogenic tobacco specific N'-nitrosamines.
Isonicoteine Description
Source: The aerial part of Anabasis aphylla L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.4025 mL 32.0123 mL 64.0246 mL 128.0492 mL 160.0615 mL
5 mM 1.2805 mL 6.4025 mL 12.8049 mL 25.6098 mL 32.0123 mL
10 mM 0.6402 mL 3.2012 mL 6.4025 mL 12.8049 mL 16.0061 mL
50 mM 0.128 mL 0.6402 mL 1.2805 mL 2.561 mL 3.2012 mL
100 mM 0.064 mL 0.3201 mL 0.6402 mL 1.2805 mL 1.6006 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Asian Nat Prod Res. 2008 Nov-Dec;10(11-12):1093-5.
Alkaloids from Anabasis aphylla L.[Pubmed: 19031252]

METHODS AND RESULTS:
A new pyridine alkaloid 1, together with three known alkaloids N-methylanabasine (2), anabasamine (3), and Isonicoteine (4), was isolated from the aerial part of Anabasis aphylla L.
CONCLUSIONS:
Their structures were elucidated by spectroscopic analysis.
(20S)-Protopanaxatriol

Catalog No: CFN90564
CAS No: 34080-08-5
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Daidzin 6''-O-malonate

Catalog No: CFN91028
CAS No: 124590-31-4
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Clinopodiside A

Catalog No: CFN90479
CAS No: 142809-89-0
Price: $122/20mg
Platycodin D3

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CAS No: 67884-03-1
Price: $318/10mg
Ginsenoside Rd2 (Quinquenoside L10)

Catalog No: CFN95231
CAS No: 83480-64-2
Price: $318/10mg
Dehydroglyasperin C

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Isopsoralenoside

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