Science | Nature | Cell | View More
Natural Products
Isopteleine
Isopteleine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Isopteleine
Price:
CAS No.: 2181-84-2
Catalog No.: CFN96763
Molecular Formula: C13H11NO3
Molecular Weight: 229.23 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The roots of Dictamnus angustifolius G.Don ex Sweet .
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Rio de Janeiro State University (Brazil)
  • Monash University Malaysia (Malaysia)
  • University of Brasilia (Brazil)
  • Massachusetts General Hospital (USA)
  • Centralised Purchases Unit (CPU... (India)
  • Ain Shams University (Egypt)
  • Universit?t Basel (Switzerland)
  • Universidade Federal de Pernamb... (Brazil)
  • Indian Institute of Science (India)
  • University of Toronto (Canada)
  • The Vancouver Prostate Centre (... (Canada)
  • More...
Package
Featured Products
(-)-Gallocatechin gallate

Catalog No: CFN99571
CAS No: 4233-96-9
Price: $60/20mg
Protodioscin

Catalog No: CFN99517
CAS No: 55056-80-9
Price: $50/20mg
20(R)-Ginsenoside Rh2

Catalog No: CFN90340
CAS No: 112246-15-8
Price: $70/20mg
Cyclo(Pro-Val)

Catalog No: CFN90275
CAS No: 5654-87-5
Price: $238/10mg
1-O-Acetylbritannilactone

Catalog No: CFN89438
CAS No: 33627-41-7
Price: $218/20mg
Gypenoside L

Catalog No: CFN91854
CAS No: 94987-09-4
Price: $268/5mg
Uridine

Catalog No: CFN97000
CAS No: 58-96-8
Price: $30/20mg
Cannabidivarin

Catalog No: CFN89253
CAS No: 24274-48-4
Price: $ / mg
1-Caffeoylquinic acid

Catalog No: CFN99121
CAS No: 1241-87-8
Price: $350/10mg
Cannabiscitrin

Catalog No: CFN95278
CAS No: 520-14-9
Price: $318/5mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Isopteleine shows weak cytotoxic activities against human breast cancer cells (MCF7).
In vitro:
Chin J Nat Med. 2014 Mar;12(3):222-4.
A new quinoline alkaloid from the roots of Dictamnus angustifolius.[Pubmed: 24702810]
To investigate the quinoline alkaloids from the roots of Dictamnus angustifolius G.Don ex Sweet (Rutaceae).
METHODS AND RESULTS:
The quinoline alkaloids were isolated by various column chromatographic methods and their structures were elucidated on the basis of spectral analysis. A new quinoline alkaloid, 5-methoxylrobustine (1), along with five known quinoline alkaloids were obtained, and their structures were identified as dictamnine (2), robustine (3), Isopteleine (4), γ-fagarine (5), and skimmianine (6). Cytotoxicity testing of these alkaloids showed that all of them had weak cytotoxic activities against human breast cancer cells (MCF7).
CONCLUSIONS:
Compound 1 is a new quinoline alkaloid. Alkaloid 3 showed stronger anti-proliferation effect than the other alkaloids.
Isopteleine Description
Source: The roots of Dictamnus angustifolius G.Don ex Sweet .
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Taxezopidine H

Catalog No: CFN95562
CAS No: 205440-23-9
Price: $318/5mg
Mucronulatol

Catalog No: CFN95386
CAS No: 20878-98-2
Price: $318/5mg
Glicoricone

Catalog No: CFN95063
CAS No: 161099-37-2
Price: $318/5mg
Cannabisin P

Catalog No: CFN95456
CAS No: 2756983-19-2
Price: $318/5mg
3',5-Dihydroxy-4',6,7-trimethoxyfl...

Catalog No: CFN95316
CAS No: 90850-99-0
Price: $318/5mg
Perlolyrine

Catalog No: CFN95291
CAS No: 29700-20-7
Price: $413/5mg
(Z)-Ferulic acid 4-O-beta-D-glucos...

Catalog No: CFN95546
CAS No: 94942-20-8
Price: $318/10mg
Tigloylgomisin O

Catalog No: CFN95237
CAS No: 130855-74-2
Price: $368/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.3624 mL 21.8122 mL 43.6243 mL 87.2486 mL 109.0608 mL
5 mM 0.8725 mL 4.3624 mL 8.7249 mL 17.4497 mL 21.8122 mL
10 mM 0.4362 mL 2.1812 mL 4.3624 mL 8.7249 mL 10.9061 mL
50 mM 0.0872 mL 0.4362 mL 0.8725 mL 1.745 mL 2.1812 mL
100 mM 0.0436 mL 0.2181 mL 0.4362 mL 0.8725 mL 1.0906 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
(-)-Gallocatechin gallate

Catalog No: CFN99571
CAS No: 4233-96-9
Price: $60/20mg
Protodioscin

Catalog No: CFN99517
CAS No: 55056-80-9
Price: $50/20mg
20(R)-Ginsenoside Rh2

Catalog No: CFN90340
CAS No: 112246-15-8
Price: $70/20mg
Cyclo(Pro-Val)

Catalog No: CFN90275
CAS No: 5654-87-5
Price: $238/10mg
1-O-Acetylbritannilactone

Catalog No: CFN89438
CAS No: 33627-41-7
Price: $218/20mg
Gypenoside L

Catalog No: CFN91854
CAS No: 94987-09-4
Price: $268/5mg
Uridine

Catalog No: CFN97000
CAS No: 58-96-8
Price: $30/20mg
Cannabidivarin

Catalog No: CFN89253
CAS No: 24274-48-4
Price: $ / mg
1-Caffeoylquinic acid

Catalog No: CFN99121
CAS No: 1241-87-8
Price: $350/10mg
Cannabiscitrin

Catalog No: CFN95278
CAS No: 520-14-9
Price: $318/5mg
Tags: buy Isopteleine | Isopteleine supplier | purchase Isopteleine | Isopteleine cost | Isopteleine manufacturer | order Isopteleine | Isopteleine distributor