|Description:||1. Kadsulignan L shows in vitro antiviral effects on hepatitis B virus.|
2. Kadsulignan L shows moderate platelet-activating factor (PAF) antagonistic activities with the IC50 value of 2.6 x 10(-5) M.
|Targets:||PAFR | HBV|
|Source:||The stems of Kadsura japonica|
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||2.4125 mL||12.0627 mL||24.1255 mL||48.2509 mL||60.3136 mL|
|5 mM||0.4825 mL||2.4125 mL||4.8251 mL||9.6502 mL||12.0627 mL|
|10 mM||0.2413 mL||1.2063 mL||2.4125 mL||4.8251 mL||6.0314 mL|
|50 mM||0.0483 mL||0.2413 mL||0.4825 mL||0.965 mL||1.2063 mL|
|100 mM||0.0241 mL||0.1206 mL||0.2413 mL||0.4825 mL||0.6031 mL|
Chem Biodivers. 2007 May;4(5):966-72.
|Dibenzocyclooctane lignans from the stems of Kadsura induta and their antiviral effect on hepatitis B virus.[Pubmed: 17511012]|
|Two new dibenzocyclooctane lignans, kadsurindutins A (1) and B (2), were isolated from the stems of Kadsura induta, together with the known, structurally related lignans schisantherin L (3), schisantherin P (4), Kadsulignan L (5), and neokadsuranin (6). Their structures and configurations were elucidated by spectroscopic methods (UV, ORD, CD, IR, 1D- and 2D-NMR) in combination with mass-spectrometric (HR-MS) techniques. Compounds 1, 5, and 6 showed in vitro antiviral effects on hepatitis B virus.|
J Asian Nat Prod Res. 1998;1(2):125-31.
|Lignans from Kadsura angustifolia.[Pubmed: 11261213 ]|
|A new dibenzocyclooctadiene lignan named angustifolin D (1) together with four known lignans: Kadsulignan L (2), kadsulignan N (3), schisantherin P (4) and meso-dihydroguaiaretic acid (5) were isolated from the stems of Kadsura angustifolia. Their structures and stereochemistries were elucidated by spectral studies. Compounds 2 and 5 showed moderate platelet-activating factor (PAF) antagonistic activities with IC50 values of 2.6 x 10(-5) and 4.1 x 10(-5) M, respectively.|