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Koumine N-oxide
Koumine N-oxide
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Koumine N-oxide
Price:
CAS No.: 113900-75-7
Catalog No.: CFN97937
Molecular Formula: C20H22N2O2
Molecular Weight: 322.4 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Gelsemium elegans
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Koumine N-oxide is a natural product from Gelsemium elegans.
Koumine N-oxide Description
Source: The herbs of Gelsemium elegans
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1017 mL 15.5087 mL 31.0174 mL 62.0347 mL 77.5434 mL
5 mM 0.6203 mL 3.1017 mL 6.2035 mL 12.4069 mL 15.5087 mL
10 mM 0.3102 mL 1.5509 mL 3.1017 mL 6.2035 mL 7.7543 mL
50 mM 0.062 mL 0.3102 mL 0.6203 mL 1.2407 mL 1.5509 mL
100 mM 0.031 mL 0.1551 mL 0.3102 mL 0.6203 mL 0.7754 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Tetrahedron, 1988 , 44 (16) :5075-5094.
Studies on the indole alkaloids of gelsem1um elegans (thailand): structure elucidation and proposal of biogenetic route[Reference: WebLink]

METHODS AND RESULTS:
Chemical investigation of the roots of collected in Thailand resulted in the isolation of the new indole alkaloids, 16-epi-voacarpine, 19-hydroxydihydrogelsevirine, and 19-(Z)-taberpsychine, along with eight known bases.
CONCLUSIONS:
Among them, the structure of “akuammidine” and koumidine were revised to have 19-(Z) ethylidene configuration. From the seeds of 14-hydroxygelsedine was obtained. Furthermore, three new alkaloids, Koumine N-oxide, gelsemine N-oxide, and 19-oxo-gelsenicine, were found from the leaves of . A new and plausible biogenetic route of gelsemium alkaloids is proposed.
Angoroside C

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Sodium houttuyfonate

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CAS No: 1847-58-1
Price: $50/20mg
Sinomenine

Catalog No: CFN99508
CAS No: 115-53-7
Price: $30/20mg
Carnosol

Catalog No: CFN99956
CAS No: 5957-80-2
Price: $80/20mg
Dehydroglyasperin C

Catalog No: CFN96483
CAS No: 199331-35-6
Price: $ / mg
Tetramethylpyrazine

Catalog No: CFN99909
CAS No: 1124-11-4
Price: $30/20mg
Bakuchiol

Catalog No: CFN99047
CAS No: 10309-37-2
Price: $40/20mg
Caftaric acid

Catalog No: CFN00384
CAS No: 67879-58-7
Price: $138/20mg
Asiaticoside

Catalog No: CFN99912
CAS No: 16830-15-2
Price: $40/20mg
Tilianin

Catalog No: CFN92764
CAS No: 4291-60-5
Price: $218/20mg
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