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Lemannine
Lemannine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Lemannine
Price:
CAS No.: 58480-54-9
Catalog No.: CFN92839
Molecular Formula: C15H22N2O
Molecular Weight: 246.4 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Cryst.
Source: The herbs of Ammothamnus lehmannii
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Standard reference
In vitro:
AAPS PharmSciTech. 2010 Sep;11(3):1350-8.
Preparation and in vitro evaluation of ethosomal total alkaloids of Sophora alopecuroides loaded by a transmembrane pH-gradient method.[Pubmed: 20740333]
A novel transmembrane pH gradient active loading method to prepare alkaloids binary ethosomes was developed in this work. Using this novel method, binary ethosomes containing total alkaloids extracted from Sophora alopecuroides (TASA) were prepared successfully at the temperature below the phase transition temperature (Tc) of the phosphatidyl choline (PC). Several factors affecting this method were investigated.
METHODS AND RESULTS:
The qualities of the TASA binary ethosomes were characterized by the shape, particle size, and encapsulation efficiency (EE). The percutaneous absorption study of TASA binary ethosomes was performed using confocal laser scanning microscopy and Franz diffusion cells. The results showed that more than 90% sophoridine, 47% matrine, 35% sophocarpine, and 32% Lemannine in TASA were entrapped within 1 h at 40°C, with an efficiency improvement of 8.87, 8.10, 7.63, and 7.78-fold than those observed in passive loading method. Transdermal experiments showed that the penetration depth and fluorescence intensity of Rhodamine B from binary ethosome prepared by pH gradient active loading method were much greater than that from binary ethosome prepared by passive loading method or hydroalcoholic solution.
CONCLUSIONS:
These results suggested transmembrane pH gradient active loading method may be an effective method to prepare alkaloids ethosomal systems at the temperatures below the Tc of PC.
Lemannine Description
Source: The herbs of Ammothamnus lehmannii
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.0584 mL 20.2922 mL 40.5844 mL 81.1688 mL 101.461 mL
5 mM 0.8117 mL 4.0584 mL 8.1169 mL 16.2338 mL 20.2922 mL
10 mM 0.4058 mL 2.0292 mL 4.0584 mL 8.1169 mL 10.1461 mL
50 mM 0.0812 mL 0.4058 mL 0.8117 mL 1.6234 mL 2.0292 mL
100 mM 0.0406 mL 0.2029 mL 0.4058 mL 0.8117 mL 1.0146 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Luteolin-4'-O-glucoside

Catalog No: CFN93776
CAS No: 6920-38-3
Price: $ / mg
Nerolidol

Catalog No: CFN98638
CAS No: 7212-44-4
Price: $30/20mg
Conduritol A

Catalog No: CFN98868
CAS No: 526-87-4
Price: $258/10mg
Squalene

Catalog No: CFN99208
CAS No: 111-02-4
Price: $30/20mg
Ginsenoside Rg2

Catalog No: CFN99968
CAS No: 52286-74-5
Price: $60/20mg
Pectolinarigenin

Catalog No: CFN99010
CAS No: 520-12-7
Price: $138/20mg
Vanillic acid

Catalog No: CFN99331
CAS No: 121-34-6
Price: $30/20mg
Asperglaucide

Catalog No: CFN98937
CAS No: 56121-42-7
Price: $238/5mg
(-)-Asarinin

Catalog No: CFN90144
CAS No: 133-04-0
Price: $128/20mg
Tetrahydropalmatine

Catalog No: CFN99553
CAS No: 2934-97-6
Price: $30/20mg
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