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Malvidin chloride
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Product Name Malvidin chloride
Price: $398 / 10mg
CAS No.: 643-84-5
Catalog No.: CFN92035
Molecular Formula: C17H15ClO7
Molecular Weight: 366.8 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The fruits of Vaccinium myrtillus
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $219.9 / In-stock
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Malvidin chloride has anti-spermatogenic, and antioxidant activities. It can prevent endothelial dysfunction by inhibiting ROS and XO-1.
Targets: ROS | XO-1
In vitro:
Food Science, 2015.
Antioxidant Effect of Blueberry Malvidin Chloride in Human Umbilical Vein Endothelial Cells.[Reference: WebLink]
The effect of Malvidin chloride(Mv-Cl) extracted from blueberries on the amounts of reactive oxygen species(ROS) and xanthine oxidase-1(XO-1) in human umbilical vein endothelial cells(HUVECs) was investigated to explore the antioxidant potential of the anthocyanin compound.
METHODS AND RESULTS:
HUVECs were in vitro cultured in the presence of Mv-Cl(1, 5 and 10 μmol/L), angiotensinⅡ(Ang II, 10-2 μmol/L) and their combination, respectively. DMSO was used as control. The ROS content in the cells was detected by immunofluorescence. The soluble XO-1 protein content in the cell culture supernatant was detected by ELISA. The protein expression of XO-1 in the cells was assessed by Western blotting. The content of ROS and the protein expression of XO-1 in HUVECs were decreased when treated with low concentration of Mv-Cl. Ang II significantly increased ROS and XO-1 content, and Mv-Cl appeared to specifically down-regulate the production of ROS and XO-1.
CONCLUSIONS:
Malvidin chloride can prevent endothelial dysfunction by inhibiting ROS and XO-1. Therefore, blueberry anthocyanin may be a new inhibitor of ROS and XO-1, which provides a theoretical basis for the application of blueberry anthocyanins to prevent cardiovascular diseases as a functional food or nutraceutical ingredient.
Nutrition and Cancer, 2011, 63(7):1044-1052.
Inhibitory Effect of Antioxidant Extracts From Various Potatoes on the Proliferation of Human Colon and Liver Cancer Cells.[Reference: WebLink]
Antioxidant extracts from 5 potato lines were evaluated for antioxidant activity, total phenolics, chlorogenic acid, anthocyanin content, and in vitro anticancer capacity.
METHODS AND RESULTS:
Analysis showed that Mexican wild species S. pinnatisectum had the highest antioxidant activity, total phenolic, and chlorogenic acid content. The proliferation of colon cancer and liver cancer cells was significantly inhibited by potato antioxidant extracts. The highest antiproliferative activity was observed in extracts of S. pinnatisectum and the lowest in Northstar. An inverse correlation was found between total phenolics and the EC50 of colon cancer cell (R2 = 0.9303), as well as liver cancer cell proliferation (R2 = 0.8992). The relationship between antioxidant activity and EC50 of colon cancer/liver cancer cell proliferation was significant (R2 = 0.8144; R2 = 0.956, respectively).
CONCLUSIONS:
A significant difference in inhibition of cancer cells (P < 0.01) existed between the 3 polyphenols: chlorogenic acid, pelargonidin chloride, and Malvidin chloride, suggesting that chlorogenic acid was a critical factor in the antiproliferation of colon cancer and liver cancer cells.
In vivo:
International Journal of Andrology, 1990, 13(3):207-215.
Anti-spermatogenic activity of malvidin chloride in langur monkeys (Presbytis entellus entellus Dufresne).[Reference: WebLink]
Malvidin chloride (MC) a colouring agent from flowers of Malvaviscus conzattii Greenum was studied for male anti-fertility effects in adult langur monkeys (Presbytis entellus entellus Dufresne).
METHODS AND RESULTS:
When fed 50 mg MC kg-1 for a period of 60 days, inhibition of spermatogenesis resulted. The weights of testes and epididymides were reduced and there was atrophy of the Leydig cells. In the epididymis, epithelial cell heights were reduced after MC-treatment. Conspicuous shrinkage of seminiferous tubules and Leydig cell nuclei were evident. Depletion of total proteins, RNA, sialic acid, alkaline/acid phosphatase activity in testes and epididymides with the elevation of testicular levels of cholesterol and glycogen also occurred. Blood/serum analysis and haematology of MC-treated langur monkeys revealed that all of the clinically important parameters were well within the normal range. The slightly increased bilirubin concentration and alkaline phosphatase activity returned to normal range within 30 days of the last dose of MC. The anti-spermatogenic activity of MC in langur monkeys is discussed.
Malvidin chloride Description
Source: The fruits of Vaccinium myrtillus
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7263 mL 13.6314 mL 27.2628 mL 54.5256 mL 68.157 mL
5 mM 0.5453 mL 2.7263 mL 5.4526 mL 10.9051 mL 13.6314 mL
10 mM 0.2726 mL 1.3631 mL 2.7263 mL 5.4526 mL 6.8157 mL
50 mM 0.0545 mL 0.2726 mL 0.5453 mL 1.0905 mL 1.3631 mL
100 mM 0.0273 mL 0.1363 mL 0.2726 mL 0.5453 mL 0.6816 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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